4uxq

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m (Protected "4uxq" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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==FGFR4 in complex with Ponatinib==
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<StructureSection load='4uxq' size='340' side='right' caption='[[4uxq]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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The entry 4uxq is ON HOLD
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4uxq]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UXQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UXQ FirstGlance]. <br>
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Authors: Tucker, J., Klein, T., Breed, J., Breeze, A., Overman, R., Phillips, C., Norman, R.A.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0LI:3-(IMIDAZO[1,2-B]PYRIDAZIN-3-YLETHYNYL)-4-METHYL-N-{4-[(4-METHYLPIPERAZIN-1-YL)METHYL]-3-(TRIFLUOROMETHYL)PHENYL}BENZAMIDE'>0LI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr>
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Description: FGFR4 in complex with Ponatinib
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uxq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uxq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4uxq RCSB], [http://www.ebi.ac.uk/pdbsum/4uxq PDBsum]</span></td></tr>
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</table>
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__TOC__
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</StructureSection>
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[[Category: Receptor protein-tyrosine kinase]]
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[[Category: Breed, J]]
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[[Category: Breeze, A]]
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[[Category: Klein, T]]
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[[Category: Norman, R A]]
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[[Category: Overman, R]]
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[[Category: Phillips, C]]
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[[Category: Tucker, J]]
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[[Category: Kinase dfg-out fgfr inhibitor complex]]
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[[Category: Transferase]]

Revision as of 09:49, 3 December 2014

FGFR4 in complex with Ponatinib

4uxq, resolution 1.85Å

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