1mem
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | [[Image:1mem.gif|left|200px]] | + | [[Image:1mem.gif|left|200px]] |
| - | + | ||
| - | '''CRYSTAL STRUCTURE OF CATHEPSIN K COMPLEXED WITH A POTENT VINYL SULFONE INHIBITOR''' | + | {{Structure |
| + | |PDB= 1mem |SIZE=350|CAPTION= <scene name='initialview01'>1mem</scene>, resolution 1.8Å | ||
| + | |SITE= <scene name='pdbsite=CAT:Description+Not+Provided'>CAT</scene> | ||
| + | |LIGAND= <scene name='pdbligand=BZP:N1-CARBOXYPIPERAZINE'>BZP</scene> and <scene name='pdbligand=BNS:HYDROSULFONYLBENZENE'>BNS</scene> | ||
| + | |ACTIVITY= [http://en.wikipedia.org/wiki/Cathepsin_K Cathepsin K], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.38 3.4.22.38] | ||
| + | |GENE= | ||
| + | }} | ||
| + | |||
| + | '''CRYSTAL STRUCTURE OF CATHEPSIN K COMPLEXED WITH A POTENT VINYL SULFONE INHIBITOR''' | ||
| + | |||
==Disease== | ==Disease== | ||
| Line 7: | Line 16: | ||
==About this Structure== | ==About this Structure== | ||
| - | 1MEM is a [ | + | 1MEM is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MEM OCA]. |
==Reference== | ==Reference== | ||
| - | Crystal structure of human cathepsin K complexed with a potent inhibitor., McGrath ME, Klaus JL, Barnes MG, Bromme D, Nat Struct Biol. 1997 Feb;4(2):105-9. PMID:[http:// | + | Crystal structure of human cathepsin K complexed with a potent inhibitor., McGrath ME, Klaus JL, Barnes MG, Bromme D, Nat Struct Biol. 1997 Feb;4(2):105-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9033587 9033587] |
[[Category: Cathepsin K]] | [[Category: Cathepsin K]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| Line 24: | Line 33: | ||
[[Category: protease]] | [[Category: protease]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:42:32 2008'' |
Revision as of 10:42, 20 March 2008
| |||||||
| , resolution 1.8Å | |||||||
|---|---|---|---|---|---|---|---|
| Sites: | |||||||
| Ligands: | and | ||||||
| Activity: | Cathepsin K, with EC number 3.4.22.38 | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
CRYSTAL STRUCTURE OF CATHEPSIN K COMPLEXED WITH A POTENT VINYL SULFONE INHIBITOR
Disease
Known disease associated with this structure: Pycnodysostosis OMIM:[601105]
About this Structure
1MEM is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Crystal structure of human cathepsin K complexed with a potent inhibitor., McGrath ME, Klaus JL, Barnes MG, Bromme D, Nat Struct Biol. 1997 Feb;4(2):105-9. PMID:9033587
Page seeded by OCA on Thu Mar 20 12:42:32 2008
