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Phosphotransferase

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{{#tree:id=OrganizedByTopic|openlevels=0|
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===Phosphotransferase===
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*'''Phosphotransferase'''
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[[3our]] – PT IIA + pyruvate decarboxylase – ''Vibrio vulnificus''<BR />
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**[[3our]] – PT IIA + pyruvate decarboxylase – ''Vibrio vulnificus''<BR />
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[[2l5h]], [[2kx9]] - EcPT I - ''Escherichia coli'' – NMR<BR />
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**[[2l5h]], [[2kx9]] - EcPT I - ''Escherichia coli'' – NMR<BR />
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[[2xdf]] - EcPT I+ phosphocarrier protein HPR – NMR<BR />
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**[[2xdf]] - EcPT I+ phosphocarrier protein HPR – NMR<BR />
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[[3oxp]] – PT II – ''Yersinia pestis''<BR />
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**[[3oxp]] – PT II – ''Yersinia pestis''<BR />
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[[3ci6]] – PT GAF domain – ''Acinetobacter''<BR />
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**[[3ci6]] – PT GAF domain – ''Acinetobacter''<BR />
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[[2ooc]], [[4fpp]] – PT histidine – ''Caulobacter crescentus''<BR />
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**[[2ooc]], [[4fpp]] – PT histidine – ''Caulobacter crescentus''<BR />
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[[3ipj]] – PT IIABC – ''Clostridium difficile''<BR />
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**[[3ipj]] – PT IIABC – ''Clostridium difficile''<BR />
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[[2f9h]] - EfPT IIA – ''Enterococcus faecalis''<BR />
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**[[2f9h]] - EfPT IIA – ''Enterococcus faecalis''<BR />
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[[1c02]] - PT - yeast<br />
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**[[1c02]] - PT - yeast<br />
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[[3n9x]] – PT – ''Plasmodium berghei''<br />
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**[[3n9x]] – PT – ''Plasmodium berghei''<br />
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**[[1fyn]] – PT SH3 domain + polyproline peptide - human<br />
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===Aminoglycoside phosphotransferase===
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*'''Aminoglycoside phosphotransferase'''
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[[3ovc]] - EcAGPT IA<BR />
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**[[3ovc]] - EcAGPT IA<BR />
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[[3r6z]], [[3uzr]] - EcAGPT IB<BR />
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**[[3r6z]], [[3uzr]] - EcAGPT IB<BR />
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[[3q2m]], [[3i1a]] – LpAGPT IA – ''Legionella pneumophila''<BR />
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**[[3q2m]], [[3i1a]] – LpAGPT IA – ''Legionella pneumophila''<BR />
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[[1nd4]] – KpAGPT IIA – ''Klebsiella pneumoniae''<BR />
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**[[1nd4]] – KpAGPT IIA – ''Klebsiella pneumoniae''<BR />
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[[1qhn]] – SvAGPT – ''Streptomyces venezuelae''<BR />
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**[[1qhn]] – SvAGPT – ''Streptomyces venezuelae''<BR />
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[[3sgc]], [[3r7z]], [[3n4t]], [[3n4u]], [[3n4v]] ,[[4dbx]], [[4de4]] - EncAGPT ID – ''Enterococcus casseliflavus''<BR />
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**[[3sgc]], [[3r7z]], [[3n4t]], [[3n4u]], [[3n4v]] ,[[4dbx]], [[4de4]] - EncAGPT ID – ''Enterococcus casseliflavus''<BR />
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[[1j7i]] - EfAGPT IIIA
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**[[1j7i]] - EfAGPT IIIA
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===Aminoglycoside phosphotransferase complex with nucleotide===
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*Aminoglycoside phosphotransferase complex with nucleotide
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[[3r70]], [[4dca]] - EcAGPT IB + ADP<BR />
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**[[3r70]], [[4dca]] - EcAGPT IB + ADP<BR />
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[[3r78]] - EcAGPT IB + ATP<BR />
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**[[3r78]] - EcAGPT IB + ATP<BR />
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[[1qhx]] - SvAGPT + ATP<BR />
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**[[1qhx]] - SvAGPT + ATP<BR />
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[[3i0q]] - LpAGPT IA + AMP<BR />
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**[[3i0q]] - LpAGPT IA + AMP<BR />
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[[1j7l]] - EfAGPT IIIA + ADP <BR />
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**[[1j7l]] - EfAGPT IIIA + ADP <BR />
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[[1j7u]] - EfAGPT IIIA + AMP-PNP <br />
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**[[1j7u]] - EfAGPT IIIA + AMP-PNP <br />
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[[4ej7]] - AGPT IA + ATP – ''Acinetobacter baumanii''<br />
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**[[4ej7]] - AGPT IA + ATP – ''Acinetobacter baumanii''<br />
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[[4dt8]], [[4dt9]] - EncAGPT ID + nucleotide<br />
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**[[4dt8]], [[4dt9]] - EncAGPT ID + nucleotide<br />
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[[4dta]], [[4dtb]] - EncAGPT ID (mutant) + nucleotide
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**[[4dta]], [[4dtb]] - EncAGPT ID (mutant) + nucleotide
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===Aminoglycoside phosphotransferase complex with antibiotic<br />===
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*Aminoglycoside phosphotransferase complex with antibiotic
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[[3hav]], [[3ham]] - EfAGPT + ATP + antibiotic <BR />
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**[[3hav]], [[3ham]] - EfAGPT + ATP + antibiotic <BR />
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[[3h8p]], [[3tm0]] - EfAGPT + AMP-PNP + antibiotic<br />
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**[[3h8p]], [[3tm0]] - EfAGPT + AMP-PNP + antibiotic<br />
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[[2b0q]], [[1l8t]] - EfAGPT IIIA + ADP + antibiotic<br />
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**[[2b0q]], [[1l8t]] - EfAGPT IIIA + ADP + antibiotic<br />
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[[3r80]], [[3r81]] - EcAGPT ID + antibiotic<br />
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**[[3r80]], [[3r81]] - EcAGPT ID + antibiotic<br />
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[[1grq]], [[1grr]], [[1qhs]] - SvAGPT + antibiotic<br />
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**[[1grq]], [[1grr]], [[1qhs]] - SvAGPT + antibiotic<br />
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[[1qhy]] - SvAGPT + ATPγ + antibiotic<br />
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**[[1qhy]] - SvAGPT + ATPγ + antibiotic<br />
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[[3sg8]], [[3sg9]], [[4dfb]], [[4dfu]] - EncAGPT ID + antibiotic<br />
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**[[3sg8]], [[3sg9]], [[4dfb]], [[4dfu]] - EncAGPT ID + antibiotic<br />
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[[3i0o]] - LpAGPT IA + ADP + antibiotic<br />
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**[[3i0o]] - LpAGPT IA + ADP + antibiotic<br />
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[[4feu]], [[4fev]], [[4few]], [[4fex]], [[4gkh]], [[4gki]] - LpAGPT IA + inhibitor + antibiotic
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**[[4feu]], [[4fev]], [[4few]], [[4fex]], [[4gkh]], [[4gki]] - LpAGPT IA + inhibitor + antibiotic
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===Aminoglycoside phosphotransferase complex with inhibitor===
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*Aminoglycoside phosphotransferase complex with inhibitor
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[[2bkk]], [[3q2j]] - EfAGPT IIIA + inhibitor
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**[[2bkk]], [[3q2j]] - EfAGPT IIIA + inhibitor
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===Phosphoenolpyruvate-protein phosphotransferase===
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*'''Phosphoenolpyruvate-protein phosphotransferase'''
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[[2xz7]] – TtPEP PEP-binding domain + phosphoenolpyruvate – ''Thermoanaerobacter tengcongensis''<BR />
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**[[2xz7]] – TtPEP PEP-binding domain + phosphoenolpyruvate – ''Thermoanaerobacter tengcongensis''<BR />
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[[2xz9]] - TtPEP PEP-binding domain + pyruvate<BR />
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**[[2xz9]] - TtPEP PEP-binding domain + pyruvate<BR />
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[[3nbm]] – PEP lactose-specific IIBC – ''Streptococcus pneumoniae''<BR />
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**[[3nbm]] – PEP lactose-specific IIBC – ''Streptococcus pneumoniae''<BR />
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[[2l2q]] - PEP cellbiose-specific IIB – ''Borrelia burgdorferi'' – NMR<BR />
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**[[2l2q]] - PEP cellbiose-specific IIB – ''Borrelia burgdorferi'' – NMR<br />
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[[3k1s]] - PEP cellbiose-specific IIA – ''Bacillus anthracis''<BR />
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**[[3k1s]] - PEP cellbiose-specific IIA – ''Bacillus anthracis''<br />
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[[2kyr]] – EcPEP fructose-specific IIB<BR />
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**[[2kyr]] – EcPEP fructose-specific IIB<br />
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[[2r4q]] - BsPEP fructose-specific IIABC – ''Bacillus subtilis''<BR />
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**[[2r4q]] - BsPEP fructose-specific IIABC – ''Bacillus subtilis''<br />
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[[2r48]] - BsPEP fructose-specific IIB<BR />
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**[[2r48]] - BsPEP fructose-specific IIB<br />
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[[1vsq]], [[2jzh]], [[2jzn]], [[2jzo]] - EcPEP mannose-specific IIA - NMR<BR />
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**[[1vsq]], [[2jzh]], [[2jzn]], [[2jzo]] - EcPEP mannose-specific IIA - NMR<br />
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[[3bp3]] - EcPEP glucose-specific IIB<BR />
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**[[3bp3]] - EcPEP glucose-specific IIB<br />
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[[1o53]] - EcPEP glucose-specific IIA N terminal – NMR<BR />
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**[[1o53]] - EcPEP glucose-specific IIA N terminal – NMR<br />
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[[1ggr]] - EcPEP glucose-specific IIA + phosphocarrier protein HPR – NMR<BR />
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**[[1ggr ]]- EcPEP glucose-specific IIA + phosphocarrier protein HPR – NMR<br />
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[[3bp8]] - EcPEP glucose-specific IIB + NAGC-like transcriptional regulator<BR />
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**[[3bp8]] - EcPEP glucose-specific IIB + NAGC-like transcriptional regulator<br />
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[[3eye]] - EcPEP acetylgalactosamine-specific IIB<BR />
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**[[3eye]] - EcPEP acetylgalactosamine-specific IIB<br />
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[[2oq3]], [[1vrv]] - EcPEP mannitol-specific IIA<BR />
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**[[2oq3]], [[1vrv]] - EcPEP mannitol-specific IIA<br />
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[[1vkr]] - EcPEP mannitol-specific IIABC – NMR<BR />
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**[[1vkr]] - EcPEP mannitol-specific IIABC – NMR<br />
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[[1j6t]] - EcPEP mannitol-specific IIABC + phosphocarrier protein HPR – NMR<BR />
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**[[1j6t]] - EcPEP mannitol-specific IIABC + phosphocarrier protein HPR – NMR<br />
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[[2few]] - EcPEP mannitol-specific IIA (mutant) <BR />
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**[[2few]] - EcPEP mannitol-specific IIA (mutant)<br />
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[[1wcr]] - EcPEP diacetylchitobiose-specific IIA (mutant) – NMR<BR />
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**[[1wcr]] - EcPEP diacetylchitobiose-specific IIA (mutant) – NMR<br />
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[[1h9c]] - EcPEP diacetylchitobiose-specific IIB – NMR<BR />
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**[[1h9c]] - EcPEP diacetylchitobiose-specific IIB – NMR<br />
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[[2hwg]] - EcPEP<br />
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**[[2hwg]] - EcPEP<br />
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[[3ipr]] – EfPEP gluconate-specific IIA<BR />
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**[[3ipr]] – EfPEP gluconate-specific IIA<br />
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[[3bed]] - EfPEP mannose-specific IIA<BR />
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**[[3bed]] - EfPEP mannose-specific IIA<br />
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[[1nrz]] - KpPEP sorbose-specific IIB<br />
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**[[1nrz]] - KpPEP sorbose-specific IIB<br />
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[[2hro]] – PEP – ''Staphylococcus carnosus''<br />
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**[[2hro]] – PEP – ''Staphylococcus carnosus''<br />
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[[2wqd]] - PEP (mutant) – ''Staphylococcus aureus''<br />
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**[[2wqd]] - PEP (mutant) – ''Staphylococcus aureus''<br />
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[[3trc]] - PEP (mutant) – ''Coxiella burnetii''
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**[[3trc]] - PEP (mutant) – ''Coxiella burnetii''<br />
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[[1f51]], [[1pey]], [[2ftk]] – BsPT sporulation initiation<br />
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*'''Sporulation initiation phospotransferase'''
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[[1pux]] - BsPT sporulation initiation – NMR<br />
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[[2jvi]], [[2jvj]], [[2jvk]] - BsPT sporulation initiation (mutant) – NMR<br />
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[[3q15]] - BsPT sporulation initiation + response regulator aspartate phosphatase<br />
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[[1fyn]] – PT SH3 domain + polyproline peptide - human
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**[[1f51]], [[1pey]], [[2ftk]] – BsPT sporulation initiation<br />
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**[[1pux]] - BsPT sporulation initiation – NMR<br />
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**[[2jvi]], [[2jvj]], [[2jvk]] - BsPT sporulation initiation (mutant) – NMR<br />
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**[[3q15]] - BsPT sporulation initiation + response regulator aspartate phosphatase<br />
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Revision as of 10:11, 3 December 2014

Template:STRUCTURE 3q2m

Phosphotransferase (PT) are enzymes which catalyze phosphorylation reactions. The acceptor group can be alcohol, carboxy, nitrogenous, phosphate or a pair ofd groups.

  • Aminoglycoside PT (AGPT) inactivate aminoglycoside antibiotics by phosphorylation.
  • Phosphoenolpyruvate-protein PT (PEP) catalyzes the phosphorylation of protein histidine residues.

See:

3D structures of phosphotransferase

Updated on 03-December-2014

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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