3g80
From Proteopedia
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| - | [[ | + | ==Nodamura virus protein b2, RNA-binding domain== |
| + | <StructureSection load='3g80' size='340' side='right' caption='[[3g80]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3g80]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Nodamura_virus Nodamura virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G80 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3G80 FirstGlance]. <br> | ||
| + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">B2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=12288 Nodamura virus])</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3g80 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g80 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3g80 RCSB], [http://www.ebi.ac.uk/pdbsum/3g80 PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Protein B2 from Nodamura virus (NMV B2), a member of the Nodavirus family, acts as a suppressor of RNA interference (RNAi). The N-terminal domain of NMV B2, consisting of residues 1-79, recognizes double-stranded RNA (dsRNA). The 2.5 A crystal structure of the RNA-binding domain of NMV B2 shows a dimeric, helical bundle structure. The structure shows a conserved set of RNA-binding residues compared with flock house virus B2, despite limited sequence identity. The crystal packing places the RNA-binding residues along one face of symmetry-related molecules, suggesting a potential platform for recognition of dsRNA. | ||
| - | + | Structure of the RNA-Binding Domain of Nodamura Virus Protein B2, a Suppressor of RNA Interference (dagger) , (double dagger).,Korber S, Shaik Syed Ali P, Chen JC Biochemistry. 2009 Mar 24;48(11):2307-9. PMID:19249868<ref>PMID:19249868</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| - | + | == References == | |
| - | + | <references/> | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | ||
| - | == | + | |
| - | < | + | |
[[Category: Nodamura virus]] | [[Category: Nodamura virus]] | ||
| - | [[Category: Ali, P Shaik Syed | + | [[Category: Ali, P Shaik Syed]] |
| - | [[Category: Chen, J C | + | [[Category: Chen, J C]] |
| - | [[Category: Korber, S | + | [[Category: Korber, S]] |
[[Category: Rna interference]] | [[Category: Rna interference]] | ||
[[Category: Rna-binding]] | [[Category: Rna-binding]] | ||
[[Category: Suppressor of rnai]] | [[Category: Suppressor of rnai]] | ||
[[Category: Viral protein]] | [[Category: Viral protein]] | ||
Revision as of 10:16, 3 December 2014
Nodamura virus protein b2, RNA-binding domain
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