1mh1

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[[Image:1mh1.jpg|left|200px]]<br /><applet load="1mh1" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1mh1.jpg|left|200px]]
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caption="1mh1, resolution 1.38&Aring;" />
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'''SMALL G-PROTEIN'''<br />
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{{Structure
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|PDB= 1mh1 |SIZE=350|CAPTION= <scene name='initialview01'>1mh1</scene>, resolution 1.38&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> and <scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER'>GNP</scene>
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|ACTIVITY=
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|GENE= RHO ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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}}
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'''SMALL G-PROTEIN'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1MH1 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=MG:'>MG</scene> and <scene name='pdbligand=GNP:'>GNP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MH1 OCA].
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1MH1 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MH1 OCA].
==Reference==
==Reference==
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The crystal structure of human rac1, a member of the rho-family complexed with a GTP analogue., Hirshberg M, Stockley RW, Dodson G, Webb MR, Nat Struct Biol. 1997 Feb;4(2):147-52. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9033596 9033596]
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The crystal structure of human rac1, a member of the rho-family complexed with a GTP analogue., Hirshberg M, Stockley RW, Dodson G, Webb MR, Nat Struct Biol. 1997 Feb;4(2):147-52. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9033596 9033596]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: small g-protein]]
[[Category: small g-protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:55:05 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:43:18 2008''

Revision as of 10:43, 20 March 2008

Image:1mh1.jpg


PDB ID 1mh1

Drag the structure with the mouse to rotate
, resolution 1.38Å
Ligands: and
Gene: RHO (Homo sapiens)
Coordinates: save as pdb, mmCIF, xml



SMALL G-PROTEIN


Overview

The crystal structure of human rac1, a member of the rho family of small G-proteins, complexed with the non-hydrolysable GTP analogue, guanosine-5'-(beta gamma-imino)triphosphate (GMPPNP), has been determined by X-ray analysis at a resolution of 1.38 A. Comparison with the structure of H-ras indicates that rac1 has an extra alpha-helical domain that is characteristic of the rho G proteins, and may be involved in the signalling pathway of this family.

About this Structure

1MH1 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

The crystal structure of human rac1, a member of the rho-family complexed with a GTP analogue., Hirshberg M, Stockley RW, Dodson G, Webb MR, Nat Struct Biol. 1997 Feb;4(2):147-52. PMID:9033596

Page seeded by OCA on Thu Mar 20 12:43:18 2008

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