Plasminogen activator inhibitor

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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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{{#tree:id=OrganizedByTopic|openlevels=0|
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===PAI-1===
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*Plasminogen activator inhibitor-1
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[[1c5g]], [[1lj5]] - hPAI-1 – human<br />
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**[[1c5g]], [[1lj5]] - hPAI-1 – human<br />
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[[1b3k]], [[1db2]], [[1dvm]], [[1dvn]], [[3cvm]], [[3eox]], [[3q02]], [[3q03]], [[3r4l]] - hPAI-1 (mutant)<br />
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**[[1b3k]], [[1db2]], [[1dvm]], [[1dvn]], [[3cvm]], [[3eox]], [[3q02]], [[3q03]], [[3r4l]] - hPAI-1 (mutant)<br />
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[[1a7c]], [[9pai]] – hPAI-1 (mutant) + polypeptide <br />
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**[[1a7c]], [[9pai]] – hPAI-1 (mutant) + polypeptide <br />
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[[4g8r]], [[4g8o]] – hPAI-1 + inactivator<br />
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**[[4g8r]], [[4g8o]] – hPAI-1 + inactivator<br />
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[[4ic0]] - hPAI-1 (mutant) + gallate<br />
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**[[4ic0]] - hPAI-1 (mutant) + gallate<br />
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[[3ut3]] - hPAI-1 (mutant) + inhibitor<br />
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**[[3ut3]] - hPAI-1 (mutant) + inhibitor<br />
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[[3aqh]] - hPAI-1 + inhibitor<br />
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**[[3aqh]] - hPAI-1 + inhibitor<br />
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[[1oc0]] - hPAI-1 (mutant) + vitronectin<br />
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**[[1oc0]] - hPAI-1 (mutant) + vitronectin<br />
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[[3pb1]] - hPAI-1 (mutant) + urokinase (mutant)<br />
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**[[3pb1]] - hPAI-1 (mutant) + urokinase (mutant)<br />
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[[3lw2]] – PAI-1 - mouse<br />
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**[[3lw2]] – PAI-1 - mouse<br />
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[[4kds]] – PAI-1 – trout<br />
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**[[4kds]] – PAI-1 – trout<br />
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[[4dte]] – PAI-1 – zebra fish<br />
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**[[4dte]] – PAI-1 – zebra fish<br />
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===PAI-2===
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*Plasminogen activator inhibitor-2
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[[1by7]] - hPAI-2 (mutant)<br />
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**[[1by7]] - hPAI-2 (mutant)<br />
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[[1jrr]], [[2arq]], [[2arr]] - hPAI-2 (mutant) + polypeptide
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**[[1jrr]], [[2arq]], [[2arr]] - hPAI-2 (mutant) + polypeptide
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===PAI-3===
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*Plasminogen activator inhibitor-3
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[[2ol2]] – hPAI-3<br />
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[[2hi9]] - hPAI-3 residues 25-387<br />
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[[1lq8]], [[3dy0]] – hPAI-3 cleaved
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**[[2ol2]] – hPAI-3<br />
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**[[2hi9]] - hPAI-3 residues 25-387<br />
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**[[1lq8]], [[3dy0]] – hPAI-3 cleaved
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}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 11:47, 3 December 2014

Template:STRUCTURE 1c5g

Plasminogen activator inhibitor (PAI) is a serine protease inhibitor.

  • PAI-1 inhibits tissue plasminogen activator and urokinase.
  • PAI-2 is secreted by the placenta and is present during pregnancy.
  • PAI-3 inhibits enzymes in blood coagulation.

3D Structures of plasminogen activator inhibitor

Updated on 03-December-2014

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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