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Protein phosphatase

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{{#tree:id=OrganizedByTopic|openlevels=0|
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===PP1A===
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*Protein phosphatase 1A
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[[3fxj]], [[3fxk]], [[3fxl]], [[3fxm]], [[3fxo]] – hPP1A + Mn – human<br />
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**[[3fxj]], [[3fxk]], [[3fxl]], [[3fxm]], [[3fxo]] – hPP1A + Mn – human<br />
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[[4da1]] – hPP1K + Mn<br />
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**[[4da1]] – hPP1K + Mn<br />
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[[1jk7]], [[1u32]], [[2bcd]], [[2bdx]], [[3e7a]], [[3e7b]] – hPP1 catalytic subunit + tumor-inducing toxin<br />
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**[[1jk7]], [[1u32]], [[2bcd]], [[2bdx]], [[3e7a]], [[3e7b]] – hPP1 catalytic subunit + tumor-inducing toxin<br />
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[[1fjm]] – PP1 + tumor-inducing toxin - rabbit<br />
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**[[1fjm]] – PP1 + tumor-inducing toxin - rabbit<br />
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[[3egg]] – hPP1 catalytic subunit + spinophilin<br />
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**[[3egg]] – hPP1 catalytic subunit + spinophilin<br />
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[[3hvq]] – hPP1 catalytic subunit + neuroabin<br />
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**[[3hvq]] – hPP1 catalytic subunit + neuroabin<br />
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[[3n5u]] – hPP1A catalytic subunit + retinoblastoma-associated protein<br />
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**[[3n5u]] – hPP1A catalytic subunit + retinoblastoma-associated protein<br />
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[[3v4y]] – hPP1A catalytic subunit + PP1 nuclear inhibitor<br />
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**[[3v4y]] – hPP1A catalytic subunit + PP1 nuclear inhibitor<br />
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[[4g9j]] – hPP1A catalytic subunit + peptide<br />
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**[[4g9j]] – hPP1A catalytic subunit + peptide<br />
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[[3egh]] – hPP1 catalytic subunit + spinophilin + toxin<br />
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**[[3egh]] – hPP1 catalytic subunit + spinophilin + toxin<br />
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[[1it6]] – hPP1 catalytic subunit + calyculin<br />
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**[[1it6]] – hPP1 catalytic subunit + calyculin<br />
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[[1s70]] – hPP1 catalytic subunit (mutant) + smooth muscle myosin phosphatase<br />
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**[[1s70]] – hPP1 catalytic subunit (mutant) + smooth muscle myosin phosphatase<br />
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[[2o8a]], [[2o8g]] – PP1C catalytic subunit + inhibitor - rat<br />
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**[[2o8a]], [[2o8g]] – PP1C catalytic subunit + inhibitor - rat<br />
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[[2rlt]] – PP1 regulatory subunit – pig - NMR<br />
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**[[2rlt]] – PP1 regulatory subunit – pig - NMR<br />
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===PP2A===
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*Protein phosphatase 2A
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[[1b3u]], [[2ixm]], [[2jak]], [[2g62]] – hPP2A regulatory subunit <br />
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**[[1b3u]], [[2ixm]], [[2jak]], [[2g62]] – hPP2A regulatory subunit <br />
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[[2pkg]] – hPP2A regulatory subunit + small T antigen<br />
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**[[2pkg]] – hPP2A regulatory subunit + small T antigen<br />
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[[2pf4]] – PP2A regulatory subunit + small T antigen - mouse<br />
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**[[2pf4]] – PP2A regulatory subunit + small T antigen - mouse<br />
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[[2ie3]], [[2ie4]], [[2npp]], [[2nyl]], [[2nym]], [[2iae]], [[3dw8]], [[3k7v]], [[3k7w]] – hPP2A catalytic + regulatory subunit + tumor-inducing toxin<br />
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**[[2ie3]], [[2ie4]], [[2npp]], [[2nyl]], [[2nym]], [[2iae]], [[3dw8]], [[3k7v]], [[3k7w]] – hPP2A catalytic + regulatory subunit + tumor-inducing toxin<br />
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[[3fga]] – hPP2C catalytic + regulatory subunit + tumor-inducing toxin + Sgo<br />
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**[[3fga]] – hPP2C catalytic + regulatory subunit + tumor-inducing toxin + Sgo<br />
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[[3c5w]] – hPP2A catalytic + regulatory subunit + PP2A-specific methyltransferase<br />
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**[[3c5w]] – hPP2A catalytic + regulatory subunit + PP2A-specific methyltransferase<br />
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[[3c5w]], [[3p71]] – hPP2A catalytic subunit + leucine carboxyl methyltransferase<br />
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**[[3p71]] – hPP2A catalytic subunit + leucine carboxyl methyltransferase<br />
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===PP2C===
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*Protein phosphatase 2C
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[[1a6q]] – hPP2C <br />
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**[[1a6q]] – hPP2C <br />
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[[2iq1]] – hPP2C κ <br />
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**[[2iq1]] – hPP2C κ <br />
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[[2p8e]] – hPP2C β<br />
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**[[2p8e]] – hPP2C β<br />
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[[2cm1]] – PP2C + Mn – Micobacterium tuberculosis<br />
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**[[2cm1]] – PP2C + Mn – ''Mycobacterium tuberculosis''<br />
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[[3d8k]] – PP2C – Toxoplasma gondii<br />
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**[[3d8k]] – PP2C – ''Toxoplasma gondii''<br />
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[[3jrq]], [[3kdj]], [[3nmn]] – AtPP2C + Pyl1 – Arabidopsis thaliana<br />
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**[[3jrq]], [[3kdj]], [[3nmn]] – AtPP2C + Pyl1 – ''Arabidopsis thaliana''<br />
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[[3nmt]], [[3kb3]], [[3nmv]], [[3ujl]] – AtPP2C + Pyl2<br />
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**[[3nmt]], [[3kb3]], [[3nmv]], [[3ujl]] – AtPP2C + Pyl2<br />
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[[4la7]], [[4lg5]], [4lga]], [[4lgb]] – AtPP2C + Pyl2 + ligand<br />
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**[[4la7]], [[4lg5]], [4lga]], [[4lgb]] – AtPP2C + Pyl2 + ligand<br />
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[[4ds8]] – AtPP2C + Pyl3 + Mn<br />
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**[[4ds8]] – AtPP2C + Pyl3 + Mn<br />
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[[3rt0]] – AtPP2C (mutant) + Pyl10<br />
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**[[3rt0]] – AtPP2C (mutant) + Pyl10<br />
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[[4n0g]] – AtPP2C + Pyl13<br />
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**[[4n0g]] – AtPP2C + Pyl13<br />
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[[3qn1]], [[3zvu]] – AtPP2C + Pyr1<br />
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**[[3qn1]], [[3zvu]] – AtPP2C + Pyr1<br />
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[[3ujg]] – AtPP2C + SNRK2<br />
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**[[3ujg]] – AtPP2C + SNRK2<br />
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[[3ujk]] – AtPP2C <br />
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**[[3ujk]] – AtPP2C <br />
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===PP5===
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*Protein phosphatase 5
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[[1s95]] – hPP5 catalytic domain <br />
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**[[1s95]] – hPP5 catalytic domain <br />
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[[2g62]] – hPP5 <br />
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**[[2g62]] – hPP5 <br />
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[[2bug]] – hPP5 tetratricopeptide domain + Hsp90 peptide<br />
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**[[2bug]] – hPP5 tetratricopeptide domain + Hsp90 peptide<br />
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[[3h60]] – hPP5 catalytic domain + Mn<br />
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**[[3h60]] – hPP5 catalytic domain + Mn<br />
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[[3h61]], [[3h62]], [[3h63]], [[3h64]] – hPP5 catalytic domain + Mn + inhibitor<br />
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**[[3h61]], [[3h62]], [[3h63]], [[3h64]] – hPP5 catalytic domain + Mn + inhibitor<br />
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[[3h66]] – hPP5 catalytic domain + Zn <br />
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**[[3h66]] – hPP5 catalytic domain + Zn <br />
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[[3h67]], [[3h68]], [[3h69]] – hPP5 catalytic domain + Zn + inhibitor<br />
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**[[3h67]], [[3h68]], [[3h69]] – hPP5 catalytic domain + Zn + inhibitor<br />
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}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 11:19, 4 December 2014

Template:STRUCTURE 3k7v

Protein phosphatases (PP) regular protein phosphorylation and thus are key in intracellular signal transduction processes.

  • PP1 is a serine/threonine phosphatase.
  • PP2A targets proteins in the oncogenic signaling pathways. For PP2A see also HEAT Repeat.
  • PP2C are Mg/Mn- dependent and are essential for the regulation of cell cycle and stress signaling pathways.
  • PP4 regulates a variety of cellular functions.
  • PP5 is activated by lipids and is involved in signal transduction.

3D Structures of protein phosphatase

Updated on 04-December-2014

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