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3d3x
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3d3x]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_butyricum Clostridium butyricum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D3X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3D3X FirstGlance]. <br> | <table><tr><td colspan='2'>[[3d3x]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_butyricum Clostridium butyricum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D3X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3D3X FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr> | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1t3a|1t3a]], [[1t3c|1t3c]], [[1zkw|1zkw]], [[1zkx|1zkx]], [[1zl6|1zl6]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1t3a|1t3a]], [[1t3c|1t3c]], [[1zkw|1zkw]], [[1zkx|1zkx]], [[1zl6|1zl6]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">bont/E ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1492 Clostridium butyricum])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">bont/E ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1492 Clostridium butyricum])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3d3x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d3x OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3d3x RCSB], [http://www.ebi.ac.uk/pdbsum/3d3x PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3d3x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d3x OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3d3x RCSB], [http://www.ebi.ac.uk/pdbsum/3d3x PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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SNAP-25 substrate peptide (residues 180-183) binds to but bypasses cleavage by catalytically active Clostridium botulinum neurotoxin E.,Agarwal R, Swaminathan S J Biol Chem. 2008 Sep 19;283(38):25944-51. Epub 2008 Jul 25. PMID:18658150<ref>PMID:18658150</ref> | SNAP-25 substrate peptide (residues 180-183) binds to but bypasses cleavage by catalytically active Clostridium botulinum neurotoxin E.,Agarwal R, Swaminathan S J Biol Chem. 2008 Sep 19;283(38):25944-51. Epub 2008 Jul 25. PMID:18658150<ref>PMID:18658150</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
== References == | == References == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Clostridium butyricum]] | [[Category: Clostridium butyricum]] | ||
| - | [[Category: Agarwal, R | + | [[Category: Agarwal, R]] |
| - | [[Category: Swaminathan, S | + | [[Category: Swaminathan, S]] |
[[Category: Bont e]] | [[Category: Bont e]] | ||
[[Category: Enzyme-substrate complex]] | [[Category: Enzyme-substrate complex]] | ||
Revision as of 08:30, 8 December 2014
Crystal structure of botulinum neurotoxin serotype E catalytic domain in complex with SNAP-25 substrate peptide
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