3h44

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[[Image:3h44.png|left|200px]]
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==Crystal Structure of Insulin Degrading Enzyme in Complex with macrophage inflammatory protein 1 alpha==
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<StructureSection load='3h44' size='340' side='right' caption='[[3h44]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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{{STRUCTURE_3h44| PDB=3h44 | SCENE= }}
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3h44]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H44 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3H44 FirstGlance]. <br>
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===Crystal Structure of Insulin Degrading Enzyme in Complex with macrophage inflammatory protein 1 alpha===
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DIO:1,4-DIETHYLENE+DIOXIDE'>DIO</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">IDE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), CCL3, G0S19-1, MIP1A, MIP1alpha, SCYA3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Insulysin Insulysin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.56 3.4.24.56] </span></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3h44 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3h44 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3h44 RCSB], [http://www.ebi.ac.uk/pdbsum/3h44 PDBsum]</span></td></tr>
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[[3h44]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H44 OCA].
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</table>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h4/3h44_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
*[[Insulin-Degrading Enzyme|Insulin-Degrading Enzyme]]
*[[Insulin-Degrading Enzyme|Insulin-Degrading Enzyme]]
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Insulysin]]
[[Category: Insulysin]]
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[[Category: Guo, Q.]]
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[[Category: Guo, Q]]
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[[Category: Ren, M.]]
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[[Category: Ren, M]]
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[[Category: Tang, W J.]]
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[[Category: Tang, W J]]
[[Category: Chemotaxis]]
[[Category: Chemotaxis]]
[[Category: Cytokine]]
[[Category: Cytokine]]

Revision as of 09:22, 8 December 2014

Crystal Structure of Insulin Degrading Enzyme in Complex with macrophage inflammatory protein 1 alpha

3h44, resolution 3.00Å

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