3isn

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[[Image:3isn.png|left|200px]]
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==Crystal structure of HIV-1 RT bound to A 6-vinylpyrimidine inhibitor==
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<StructureSection load='3isn' size='340' side='right' caption='[[3isn]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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{{STRUCTURE_3isn| PDB=3isn | SCENE= }}
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3isn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus Human immunodeficiency virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ISN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ISN FirstGlance]. <br>
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===Crystal structure of HIV-1 RT bound to A 6-vinylpyrimidine inhibitor===
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDM:6-ETHENYL-N,N-DIMETHYL-2-(METHYLSULFONYL)PYRIMIDIN-4-AMINE'>EDM</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ith|3ith]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gag-pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=12721 Human immunodeficiency virus])</td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3isn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3isn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3isn RCSB], [http://www.ebi.ac.uk/pdbsum/3isn PDBsum]</span></td></tr>
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[[3isn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus Human immunodeficiency virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ISN OCA].
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</table>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/is/3isn_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
*[[Reverse transcriptase|Reverse transcriptase]]
*[[Reverse transcriptase|Reverse transcriptase]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:020135654</ref><references group="xtra"/>
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[[Category: Human immunodeficiency virus]]
[[Category: Human immunodeficiency virus]]
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[[Category: Bec, G.]]
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[[Category: Bec, G]]
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[[Category: Botta, M.]]
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[[Category: Botta, M]]
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[[Category: Dumas, P.]]
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[[Category: Dumas, P]]
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[[Category: Ennifar, E.]]
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[[Category: Ennifar, E]]
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[[Category: Freisz, S.]]
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[[Category: Freisz, S]]
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[[Category: Radi, M.]]
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[[Category: Radi, M]]
[[Category: Hiv-1]]
[[Category: Hiv-1]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]

Revision as of 09:36, 8 December 2014

Crystal structure of HIV-1 RT bound to A 6-vinylpyrimidine inhibitor

3isn, resolution 2.50Å

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OCA

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