This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3huo
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | + | ==X-ray crystallographic structure of CTX-M-9 S70G in complex with benzylpenicillin== | |
| - | + | <StructureSection load='3huo' size='340' side='right' caption='[[3huo]], [[Resolution|resolution]] 1.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3huo]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HUO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HUO FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PNK:(2R,4S)-2-{(R)-CARBOXY[(PHENYLACETYL)AMINO]METHYL}-5,5-DIMETHYL-1,3-THIAZOLIDINE-4-CARBOXYLIC+ACID'>PNK</scene>, <scene name='pdbligand=PNN:PENICILLIN+G'>PNN</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3hlw|3hlw]], [[3hre|3hre]], [[3hvf|3hvf]]</td></tr> | |
| - | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">blaCTX-M-9, blaCTX-M-9a, blaCTX-M-9b ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr> | |
| - | == | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr> |
| - | [[3huo]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HUO OCA]. | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3huo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3huo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3huo RCSB], [http://www.ebi.ac.uk/pdbsum/3huo PDBsum]</span></td></tr> |
| + | </table> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hu/3huo_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
*[[Beta-lactamase|Beta-lactamase]] | *[[Beta-lactamase|Beta-lactamase]] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Beta-lactamase]] | [[Category: Beta-lactamase]] | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
| - | [[Category: Bonnet, R | + | [[Category: Bonnet, R]] |
| - | [[Category: Delmas, J | + | [[Category: Delmas, J]] |
| - | [[Category: Dubois, D | + | [[Category: Dubois, D]] |
| - | [[Category: Leyssene, D | + | [[Category: Leyssene, D]] |
| - | [[Category: Robin, F | + | [[Category: Robin, F]] |
[[Category: B-lactam]] | [[Category: B-lactam]] | ||
[[Category: Benzylpenicillin]] | [[Category: Benzylpenicillin]] | ||
| - | [[Category: Beta-lactamase]] | ||
[[Category: Blse]] | [[Category: Blse]] | ||
[[Category: Ctx-m-9]] | [[Category: Ctx-m-9]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Penicillin]] | [[Category: Penicillin]] | ||
Revision as of 09:43, 8 December 2014
X-ray crystallographic structure of CTX-M-9 S70G in complex with benzylpenicillin
| |||||||||||
Categories: Beta-lactamase | Escherichia coli | Bonnet, R | Delmas, J | Dubois, D | Leyssene, D | Robin, F | B-lactam | Benzylpenicillin | Blse | Ctx-m-9 | Hydrolase | Penicillin

