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3lpu

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[[Image:3lpu.png|left|200px]]
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==HIV integrase==
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<StructureSection load='3lpu' size='340' side='right' caption='[[3lpu]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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{{STRUCTURE_3lpu| PDB=3lpu | SCENE= }}
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3lpu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LPU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LPU FirstGlance]. <br>
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===HIV integrase===
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=976:(2S)-2-(6-CHLORO-2-METHYL-4-PHENYLQUINOLIN-3-YL)PENTANOIC+ACID'>976</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=P03:2-[3-[3-(2-HYDROXYETHOXY)PROPOXY]PROPOXY]ETHANOL'>P03</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CAF:S-DIMETHYLARSINOYL-CYSTEINE'>CAF</scene></td></tr>
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{{ABSTRACT_PUBMED_020473303}}
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1hyv|1hyv]], [[3lpt|3lpt]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lpu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lpu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3lpu RCSB], [http://www.ebi.ac.uk/pdbsum/3lpu PDBsum]</span></td></tr>
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==About this Structure==
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</table>
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[[3lpu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LPU OCA].
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lp/3lpu_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
*[[HIV integrase|HIV integrase]]
*[[HIV integrase|HIV integrase]]
*[[Retroviral Integrase|Retroviral Integrase]]
*[[Retroviral Integrase|Retroviral Integrase]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:020473303</ref><references group="xtra"/>
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[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
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[[Category: Chaltin, P.]]
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[[Category: Chaltin, P]]
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[[Category: Christ, F.]]
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[[Category: Christ, F]]
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[[Category: Debyzer, Z.]]
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[[Category: Debyzer, Z]]
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[[Category: Maeyer, M de.]]
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[[Category: Maeyer, M de]]
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[[Category: Marchand, A.]]
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[[Category: Marchand, A]]
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[[Category: Nicolet, S.]]
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[[Category: Nicolet, S]]
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[[Category: Strelkov, S V.]]
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[[Category: Strelkov, S V]]
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[[Category: Voet, A.]]
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[[Category: Voet, A]]
[[Category: Endonuclease]]
[[Category: Endonuclease]]
[[Category: Hiv]]
[[Category: Hiv]]

Revision as of 08:51, 9 December 2014

HIV integrase

3lpu, resolution 1.95Å

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