3l5h
From Proteopedia
(Difference between revisions)
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- | + | ==Crystal structure of the full ectodomain of human gp130: New insights into the molecular assembly of receptor complexes== | |
- | + | <StructureSection load='3l5h' size='340' side='right' caption='[[3l5h]], [[Resolution|resolution]] 3.60Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[3l5h]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L5H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3L5H FirstGlance]. <br> | |
- | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene></td></tr> | |
- | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3l5i|3l5i]], [[3l5j|3l5j]]</td></tr> | |
- | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">IL6ST ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3l5h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l5h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3l5h RCSB], [http://www.ebi.ac.uk/pdbsum/3l5h PDBsum]</span></td></tr> | |
- | == | + | </table> |
- | [[3l5h]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L5H OCA]. | + | == Evolutionary Conservation == |
+ | [[Image:Consurf_key_small.gif|200px|right]] | ||
+ | Check<jmol> | ||
+ | <jmolCheckbox> | ||
+ | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l5/3l5h_consurf.spt"</scriptWhenChecked> | ||
+ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
+ | <text>to colour the structure by Evolutionary Conservation</text> | ||
+ | </jmolCheckbox> | ||
+ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | ||
+ | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
*[[Interleukin receptor|Interleukin receptor]] | *[[Interleukin receptor|Interleukin receptor]] | ||
- | + | __TOC__ | |
- | + | </StructureSection> | |
- | + | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
- | [[Category: Garrett, T P.J | + | [[Category: Garrett, T P.J]] |
- | [[Category: Xu, Y | + | [[Category: Xu, Y]] |
- | [[Category: Zhang, J G | + | [[Category: Zhang, J G]] |
[[Category: Cell membrane]] | [[Category: Cell membrane]] | ||
[[Category: Disulfide bond]] | [[Category: Disulfide bond]] |
Revision as of 09:00, 9 December 2014
Crystal structure of the full ectodomain of human gp130: New insights into the molecular assembly of receptor complexes
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Categories: Homo sapiens | Garrett, T P.J | Xu, Y | Zhang, J G | Cell membrane | Disulfide bond | Fniii | Glycoprotein | Ig-like | Immune system | Immunoglobulin domain | Membrane | Phosphoprotein | Receptor | Secreted | Transmembrane