3lfa

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[[Image:3lfa.png|left|200px]]
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==Human p38 MAP Kinase in Complex with Dasatinib==
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<StructureSection load='3lfa' size='340' side='right' caption='[[3lfa]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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{{STRUCTURE_3lfa| PDB=3lfa | SCENE= }}
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3lfa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LFA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LFA FirstGlance]. <br>
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===Human p38 MAP Kinase in Complex with Dasatinib===
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1N1:N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE'>1N1</scene>, <scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3lfb|3lfb]], [[3lfc|3lfc]], [[3lfd|3lfd]], [[3lfe|3lfe]], [[3lff|3lff]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MAPK14, CSBP, CSBP1, CSBP2, CSPB1, MXI2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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==About this Structure==
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mitogen-activated_protein_kinase Mitogen-activated protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.24 2.7.11.24] </span></td></tr>
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[[3lfa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LFA OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lfa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lfa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3lfa RCSB], [http://www.ebi.ac.uk/pdbsum/3lfa PDBsum]</span></td></tr>
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</table>
==See Also==
==See Also==
*[[Mitogen-activated protein kinase|Mitogen-activated protein kinase]]
*[[Mitogen-activated protein kinase|Mitogen-activated protein kinase]]
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Mitogen-activated protein kinase]]
[[Category: Mitogen-activated protein kinase]]
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[[Category: Getlik, M.]]
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[[Category: Getlik, M]]
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[[Category: Gruetter, C.]]
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[[Category: Gruetter, C]]
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[[Category: Rauh, D.]]
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[[Category: Rauh, D]]
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[[Category: Simard, J R.]]
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[[Category: Simard, J R]]
[[Category: Atp-binding]]
[[Category: Atp-binding]]
[[Category: Dfg-out]]
[[Category: Dfg-out]]

Revision as of 09:04, 9 December 2014

Human p38 MAP Kinase in Complex with Dasatinib

3lfa, resolution 2.10Å

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