3n0t

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[[Image:3n0t.png|left|200px]]
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==Human dipeptidil peptidase DPP7 complexed with inhibitor GSK237826A==
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<StructureSection load='3n0t' size='340' side='right' caption='[[3n0t]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
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{{STRUCTURE_3n0t| PDB=3n0t | SCENE= }}
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3n0t]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N0T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3N0T FirstGlance]. <br>
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===Human dipeptidil peptidase DPP7 complexed with inhibitor GSK237826A===
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=OPY:(3S)-4-OXO-4-PIPERIDIN-1-YLBUTANE-1,3-DIAMINE'>OPY</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3jyh|3jyh]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DPP2, DPP7, QPP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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==About this Structure==
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dipeptidyl-peptidase_II Dipeptidyl-peptidase II], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.14.2 3.4.14.2] </span></td></tr>
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[[3n0t]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N0T OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3n0t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n0t OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3n0t RCSB], [http://www.ebi.ac.uk/pdbsum/3n0t PDBsum]</span></td></tr>
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</table>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n0/3n0t_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
*[[Dipeptidyl peptidase|Dipeptidyl peptidase]]
*[[Dipeptidyl peptidase|Dipeptidyl peptidase]]
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__TOC__
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</StructureSection>
[[Category: Dipeptidyl-peptidase II]]
[[Category: Dipeptidyl-peptidase II]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Arrowsmith, C H.]]
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[[Category: Arrowsmith, C H]]
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[[Category: Bochkarev, A.]]
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[[Category: Bochkarev, A]]
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[[Category: Bountra, C.]]
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[[Category: Bountra, C]]
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[[Category: Cossar, D.]]
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[[Category: Cossar, D]]
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[[Category: Crombet, L.]]
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[[Category: Crombet, L]]
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[[Category: Dobrovetsky, E.]]
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[[Category: Dobrovetsky, E]]
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[[Category: Edwards, A M.]]
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[[Category: Edwards, A M]]
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[[Category: Haffner, C.]]
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[[Category: Haffner, C]]
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[[Category: Hassell, A.]]
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[[Category: Hassell, A]]
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[[Category: Khutoreskaya, G.]]
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[[Category: Khutoreskaya, G]]
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[[Category: Pagannon, S.]]
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[[Category: Pagannon, S]]
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[[Category: SGC, Structural Genomics Consortium.]]
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[[Category: Structural genomic]]
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[[Category: Seitova, A.]]
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[[Category: Seitova, A]]
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[[Category: Shewchuk, L.]]
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[[Category: Shewchuk, L]]
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[[Category: Weigelt, J.]]
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[[Category: Weigelt, J]]
[[Category: Aminopeptidase]]
[[Category: Aminopeptidase]]
[[Category: Cleavage on pair of basic residue]]
[[Category: Cleavage on pair of basic residue]]
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[[Category: Serine protease]]
[[Category: Serine protease]]
[[Category: Sgc]]
[[Category: Sgc]]
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[[Category: Structural genomic]]
 
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[[Category: Structural genomics consortium]]
 
[[Category: Zymogen]]
[[Category: Zymogen]]

Revision as of 09:18, 9 December 2014

Human dipeptidil peptidase DPP7 complexed with inhibitor GSK237826A

3n0t, resolution 2.45Å

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