3n0t
From Proteopedia
(Difference between revisions)
Line 1: | Line 1: | ||
- | + | ==Human dipeptidil peptidase DPP7 complexed with inhibitor GSK237826A== | |
- | + | <StructureSection load='3n0t' size='340' side='right' caption='[[3n0t]], [[Resolution|resolution]] 2.45Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[3n0t]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N0T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3N0T FirstGlance]. <br> | |
- | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=OPY:(3S)-4-OXO-4-PIPERIDIN-1-YLBUTANE-1,3-DIAMINE'>OPY</scene></td></tr> | |
- | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3jyh|3jyh]]</td></tr> | |
- | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DPP2, DPP7, QPP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | |
- | == | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dipeptidyl-peptidase_II Dipeptidyl-peptidase II], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.14.2 3.4.14.2] </span></td></tr> |
- | [[3n0t]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N0T OCA]. | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3n0t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n0t OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3n0t RCSB], [http://www.ebi.ac.uk/pdbsum/3n0t PDBsum]</span></td></tr> |
+ | </table> | ||
+ | == Evolutionary Conservation == | ||
+ | [[Image:Consurf_key_small.gif|200px|right]] | ||
+ | Check<jmol> | ||
+ | <jmolCheckbox> | ||
+ | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n0/3n0t_consurf.spt"</scriptWhenChecked> | ||
+ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
+ | <text>to colour the structure by Evolutionary Conservation</text> | ||
+ | </jmolCheckbox> | ||
+ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | ||
+ | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
*[[Dipeptidyl peptidase|Dipeptidyl peptidase]] | *[[Dipeptidyl peptidase|Dipeptidyl peptidase]] | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
[[Category: Dipeptidyl-peptidase II]] | [[Category: Dipeptidyl-peptidase II]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
- | [[Category: Arrowsmith, C H | + | [[Category: Arrowsmith, C H]] |
- | [[Category: Bochkarev, A | + | [[Category: Bochkarev, A]] |
- | [[Category: Bountra, C | + | [[Category: Bountra, C]] |
- | [[Category: Cossar, D | + | [[Category: Cossar, D]] |
- | [[Category: Crombet, L | + | [[Category: Crombet, L]] |
- | [[Category: Dobrovetsky, E | + | [[Category: Dobrovetsky, E]] |
- | [[Category: Edwards, A M | + | [[Category: Edwards, A M]] |
- | [[Category: Haffner, C | + | [[Category: Haffner, C]] |
- | [[Category: Hassell, A | + | [[Category: Hassell, A]] |
- | [[Category: Khutoreskaya, G | + | [[Category: Khutoreskaya, G]] |
- | [[Category: Pagannon, S | + | [[Category: Pagannon, S]] |
- | [[Category: | + | [[Category: Structural genomic]] |
- | [[Category: Seitova, A | + | [[Category: Seitova, A]] |
- | [[Category: Shewchuk, L | + | [[Category: Shewchuk, L]] |
- | [[Category: Weigelt, J | + | [[Category: Weigelt, J]] |
[[Category: Aminopeptidase]] | [[Category: Aminopeptidase]] | ||
[[Category: Cleavage on pair of basic residue]] | [[Category: Cleavage on pair of basic residue]] | ||
Line 37: | Line 50: | ||
[[Category: Serine protease]] | [[Category: Serine protease]] | ||
[[Category: Sgc]] | [[Category: Sgc]] | ||
- | [[Category: Structural genomic]] | ||
- | [[Category: Structural genomics consortium]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] |
Revision as of 09:18, 9 December 2014
Human dipeptidil peptidase DPP7 complexed with inhibitor GSK237826A
|
Categories: Dipeptidyl-peptidase II | Homo sapiens | Arrowsmith, C H | Bochkarev, A | Bountra, C | Cossar, D | Crombet, L | Dobrovetsky, E | Edwards, A M | Haffner, C | Hassell, A | Khutoreskaya, G | Pagannon, S | Structural genomic | Seitova, A | Shewchuk, L | Weigelt, J | Aminopeptidase | Cleavage on pair of basic residue | Cytoplasmic vesicle | Glycoprotein | Hydrolase | Lysosome | Protease | Serine protease | Sgc | Zymogen