3lny

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[[Image:3lny.png|left|200px]]
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==Second PDZ domain from human PTP1E in complex with RA-GEF2 peptide==
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<StructureSection load='3lny' size='340' side='right' caption='[[3lny]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
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{{STRUCTURE_3lny| PDB=3lny | SCENE= }}
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3lny]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LNY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LNY FirstGlance]. <br>
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===Second PDZ domain from human PTP1E in complex with RA-GEF2 peptide===
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PTPN13, PNP1, PTP1E, PTPL1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), RAPGEF6, PDZGEF2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lny FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lny OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3lny RCSB], [http://www.ebi.ac.uk/pdbsum/3lny PDBsum]</span></td></tr>
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==About this Structure==
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</table>
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[[3lny]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LNY OCA].
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ln/3lny_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
*[[Tyrosine phosphatase|Tyrosine phosphatase]]
*[[Tyrosine phosphatase|Tyrosine phosphatase]]
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: CESG, Center for Eukaryotic Structural Genomics.]]
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[[Category: Structural genomic]]
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[[Category: Chang, A.]]
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[[Category: Chang, A]]
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[[Category: Ke, H.]]
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[[Category: Ke, H]]
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[[Category: Lee, A L.]]
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[[Category: Lee, A L]]
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[[Category: Phillips, G N.]]
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[[Category: Phillips, G N]]
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[[Category: Zhang, J.]]
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[[Category: Zhang, J]]
[[Category: Cell membrane]]
[[Category: Cell membrane]]
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[[Category: Center for eukaryotic structural genomic]]
 
[[Category: Cesg]]
[[Category: Cesg]]
[[Category: Cytoskeleton]]
[[Category: Cytoskeleton]]
[[Category: Guanine-nucleotide releasing factor]]
[[Category: Guanine-nucleotide releasing factor]]
[[Category: Pdz2]]
[[Category: Pdz2]]
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[[Category: Protein structure initiative]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Psi-2]]
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[[Category: Signaling protein-signaling protein complex]]
[[Category: Signaling protein-signaling protein complex]]
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[[Category: Structural genomic]]
 

Revision as of 09:50, 9 December 2014

Second PDZ domain from human PTP1E in complex with RA-GEF2 peptide

3lny, resolution 1.30Å

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