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3qaa

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[[Image:3qaa.png|left|200px]]
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==HIV-1 wild type protease with a substituted bis-Tetrahydrofuran inhibitor, GRL-044-10A==
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<StructureSection load='3qaa' size='340' side='right' caption='[[3qaa]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
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{{STRUCTURE_3qaa| PDB=3qaa | SCENE= }}
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3qaa]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QAA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3QAA FirstGlance]. <br>
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===HIV-1 wild type protease with a substituted bis-Tetrahydrofuran inhibitor, GRL-044-10A===
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=G04:(3R,3AS,4R,6AR)-4-METHOXYHEXAHYDROFURO[2,3-B]FURAN-3-YL+[(2S,3R)-3-HYDROXY-4-{[(4-METHOXYPHENYL)SULFONYL](2-METHYLPROPYL)AMINO}-1-PHENYLBUTAN-2-YL]CARBAMATE'>G04</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2ien|2ien]], [[3ok9|3ok9]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 Human immunodeficiency virus 1])</td></tr>
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==About this Structure==
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] </span></td></tr>
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[[3qaa]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QAA OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qaa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qaa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3qaa RCSB], [http://www.ebi.ac.uk/pdbsum/3qaa PDBsum]</span></td></tr>
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</table>
==See Also==
==See Also==
*[[Virus protease|Virus protease]]
*[[Virus protease|Virus protease]]
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__TOC__
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</StructureSection>
[[Category: HIV-1 retropepsin]]
[[Category: HIV-1 retropepsin]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
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[[Category: Agniswamy, J.]]
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[[Category: Agniswamy, J]]
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[[Category: Wang, Y F.]]
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[[Category: Wang, Y F]]
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[[Category: Weber, I T.]]
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[[Category: Weber, I T]]
[[Category: Aspartic acid protease]]
[[Category: Aspartic acid protease]]
[[Category: Hiv-1 protease inhibitor grl-044-10a]]
[[Category: Hiv-1 protease inhibitor grl-044-10a]]

Revision as of 10:38, 9 December 2014

HIV-1 wild type protease with a substituted bis-Tetrahydrofuran inhibitor, GRL-044-10A

3qaa, resolution 1.40Å

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