1n7s

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[[Image:1n7s.gif|left|200px]]<br /><applet load="1n7s" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1n7s.gif|left|200px]]
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caption="1n7s, resolution 1.45&Aring;" />
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'''High Resolution Structure of a Truncated Neuronal SNARE Complex'''<br />
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{{Structure
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|PDB= 1n7s |SIZE=350|CAPTION= <scene name='initialview01'>1n7s</scene>, resolution 1.45&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene> and <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>
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|ACTIVITY=
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|GENE=
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}}
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'''High Resolution Structure of a Truncated Neuronal SNARE Complex'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1N7S is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus] with <scene name='pdbligand=CA:'>CA</scene> and <scene name='pdbligand=MPD:'>MPD</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N7S OCA].
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1N7S is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N7S OCA].
==Reference==
==Reference==
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High resolution structure, stability, and synaptotagmin binding of a truncated neuronal SNARE complex., Ernst JA, Brunger AT, J Biol Chem. 2003 Mar 7;278(10):8630-6. Epub 2002 Dec 20. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12496247 12496247]
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High resolution structure, stability, and synaptotagmin binding of a truncated neuronal SNARE complex., Ernst JA, Brunger AT, J Biol Chem. 2003 Mar 7;278(10):8630-6. Epub 2002 Dec 20. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12496247 12496247]
[[Category: Protein complex]]
[[Category: Protein complex]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: neuronal snare protein complex]]
[[Category: neuronal snare protein complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:03:08 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:53:20 2008''

Revision as of 10:53, 20 March 2008

Image:1n7s.gif


PDB ID 1n7s

Drag the structure with the mouse to rotate
, resolution 1.45Å
Ligands: and
Coordinates: save as pdb, mmCIF, xml



High Resolution Structure of a Truncated Neuronal SNARE Complex


Overview

The structure of a truncated SNARE complex has been solved to 1.4-A resolution revealing a stabilizing salt bridge, sites of hydration, and conformational variability of the ionic central layer that were not observed in a previously published structure at 2.4-A resolution (Sutton, R. B., Fasshauer, D., Jahn, R., and Brunger, A. T. (1998) Nature 395, 347-353). The truncated complex lacks residues involved in phospholipid binding and denatures at a lower temperature than longer complexes as assessed by SDS and circular dichroism thermal melts. The truncated SNARE complex is monomeric, and it retains binding to synaptotagmin I.

About this Structure

1N7S is a Protein complex structure of sequences from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

High resolution structure, stability, and synaptotagmin binding of a truncated neuronal SNARE complex., Ernst JA, Brunger AT, J Biol Chem. 2003 Mar 7;278(10):8630-6. Epub 2002 Dec 20. PMID:12496247

Page seeded by OCA on Thu Mar 20 12:53:20 2008

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