3o6o
From Proteopedia
(Difference between revisions)
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| - | + | ==Crystal Structure of the N-terminal domain of an HSP90 from Trypanosoma Brucei, Tb10.26.1080 in the presence of an the inhibitor BIIB021== | |
| - | + | <StructureSection load='3o6o' size='340' side='right' caption='[[3o6o]], [[Resolution|resolution]] 2.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3o6o]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O6O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3O6O FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=94M:6-CHLORO-9-[(4-METHOXY-3,5-DIMETHYLPYRIDIN-2-YL)METHYL]-9H-PURIN-2-AMINE'>94M</scene></td></tr> | |
| - | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Tb10.26.1080 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5691 Trypanosoma brucei])</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3o6o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o6o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3o6o RCSB], [http://www.ebi.ac.uk/pdbsum/3o6o PDBsum]</span></td></tr> | |
| - | == | + | </table> |
| - | [[3o6o]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O6O OCA]. | + | == Evolutionary Conservation == |
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/o6/3o6o_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
*[[Heat Shock Proteins|Heat Shock Proteins]] | *[[Heat Shock Proteins|Heat Shock Proteins]] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Trypanosoma brucei]] | [[Category: Trypanosoma brucei]] | ||
| - | [[Category: Arrowsmith, C H | + | [[Category: Arrowsmith, C H]] |
| - | [[Category: Bochkarev, A | + | [[Category: Bochkarev, A]] |
| - | [[Category: Bountra, C | + | [[Category: Bountra, C]] |
| - | [[Category: Cossar, D | + | [[Category: Cossar, D]] |
| - | [[Category: Edwards, A M | + | [[Category: Edwards, A M]] |
| - | [[Category: Fairlamb, A H | + | [[Category: Fairlamb, A H]] |
[[Category: Ferguson, M A.J]] | [[Category: Ferguson, M A.J]] | ||
| - | [[Category: Hills, T | + | [[Category: Hills, T]] |
| - | [[Category: Hui, R | + | [[Category: Hui, R]] |
| - | [[Category: Hutchinson, A | + | [[Category: Hutchinson, A]] |
| - | [[Category: Kozieradzki, I | + | [[Category: Kozieradzki, I]] |
| - | [[Category: Li, Y | + | [[Category: Li, Y]] |
| - | [[Category: MacKenzie, C | + | [[Category: MacKenzie, C]] |
| - | [[Category: Pizarro, J C | + | [[Category: Pizarro, J C]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Sullivan, H | + | [[Category: Sullivan, H]] |
| - | [[Category: Thompson, S | + | [[Category: Thompson, S]] |
| - | [[Category: Weadge, J | + | [[Category: Weadge, J]] |
| - | [[Category: Weigelt, J | + | [[Category: Weigelt, J]] |
| - | [[Category: Wernimont, A K | + | [[Category: Wernimont, A K]] |
| - | [[Category: Wyatt, P | + | [[Category: Wyatt, P]] |
[[Category: African sleeping sickness]] | [[Category: African sleeping sickness]] | ||
[[Category: Chaperone]] | [[Category: Chaperone]] | ||
[[Category: Heat shock protein]] | [[Category: Heat shock protein]] | ||
[[Category: Sgc]] | [[Category: Sgc]] | ||
| - | [[Category: Structural genomic]] | ||
| - | [[Category: Structural genomics consortium]] | ||
[[Category: Trypanosoma]] | [[Category: Trypanosoma]] | ||
Revision as of 11:50, 9 December 2014
Crystal Structure of the N-terminal domain of an HSP90 from Trypanosoma Brucei, Tb10.26.1080 in the presence of an the inhibitor BIIB021
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Categories: Trypanosoma brucei | Arrowsmith, C H | Bochkarev, A | Bountra, C | Cossar, D | Edwards, A M | Fairlamb, A H | Ferguson, M A.J | Hills, T | Hui, R | Hutchinson, A | Kozieradzki, I | Li, Y | MacKenzie, C | Pizarro, J C | Structural genomic | Sullivan, H | Thompson, S | Weadge, J | Weigelt, J | Wernimont, A K | Wyatt, P | African sleeping sickness | Chaperone | Heat shock protein | Sgc | Trypanosoma
