3npl

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[[Image:3npl.png|left|200px]]
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==Structure of Ru(bpy)2(A-Phen)(K97C) P450 BM3 heme domain, a ruthenium modified P450 BM3 mutant==
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<StructureSection load='3npl' size='340' side='right' caption='[[3npl]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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{{STRUCTURE_3npl| PDB=3npl | SCENE= }}
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3npl]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_megaterium Bacillus megaterium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NPL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NPL FirstGlance]. <br>
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===Structure of Ru(bpy)2(A-Phen)(K97C) P450 BM3 heme domain, a ruthenium modified P450 BM3 mutant===
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=RU8:BIS(2,2-BIPYRIDINE-KAPPA~2~N~1~,N~1~)[2-IODO-N-(1,10-PHENANTHROLIN-5-YL-KAPPA~2~N~1~,N~10~)ACETAMIDE]RUTHENIUM(2+)'>RU8</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cyp102, CYP102A1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1404 Bacillus megaterium])</td></tr>
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{{ABSTRACT_PUBMED_020947800}}
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Unspecific_monooxygenase Unspecific monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.14.1 1.14.14.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3npl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3npl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3npl RCSB], [http://www.ebi.ac.uk/pdbsum/3npl PDBsum]</span></td></tr>
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==About this Structure==
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</table>
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[[3npl]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_megaterium Bacillus megaterium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NPL OCA].
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/np/3npl_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[NADPH-Cytochrome P450 Reductase|NADPH-Cytochrome P450 Reductase]]
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*[[Cytochrome P450|Cytochrome P450]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:020947800</ref><references group="xtra"/>
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[[Category: Bacillus megaterium]]
[[Category: Bacillus megaterium]]
[[Category: Unspecific monooxygenase]]
[[Category: Unspecific monooxygenase]]
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[[Category: Cheruzel, L.]]
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[[Category: Cheruzel, L]]
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[[Category: Ener, M.]]
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[[Category: Ener, M]]
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[[Category: Goodin, D B.]]
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[[Category: Goodin, D B]]
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[[Category: Gray, H B.]]
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[[Category: Gray, H B]]
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[[Category: Lee, Y T.]]
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[[Category: Lee, Y T]]
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[[Category: Winkler, J R.]]
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[[Category: Winkler, J R]]
[[Category: Electron transfer]]
[[Category: Electron transfer]]
[[Category: Mutant protein]]
[[Category: Mutant protein]]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]
[[Category: P450 bm3 heme domain]]
[[Category: P450 bm3 heme domain]]

Revision as of 12:12, 9 December 2014

Structure of Ru(bpy)2(A-Phen)(K97C) P450 BM3 heme domain, a ruthenium modified P450 BM3 mutant

3npl, resolution 2.40Å

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