3som

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[[Image:3som.png|left|200px]]
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==crystal structure of human MMACHC==
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<StructureSection load='3som' size='340' side='right' caption='[[3som]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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{{STRUCTURE_3som| PDB=3som | SCENE= }}
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3som]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SOM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3SOM FirstGlance]. <br>
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===crystal structure of human MMACHC===
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5AD:5-DEOXYADENOSINE'>5AD</scene>, <scene name='pdbligand=B12:COBALAMIN'>B12</scene>, <scene name='pdbligand=DHL:2-AMINO-ETHANETHIOL'>DHL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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{{ABSTRACT_PUBMED_022642810}}
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MMACHC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3som FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3som OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3som RCSB], [http://www.ebi.ac.uk/pdbsum/3som PDBsum]</span></td></tr>
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==About this Structure==
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</table>
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[[3som]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SOM OCA].
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== Disease ==
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[[http://www.uniprot.org/uniprot/MMAC_HUMAN MMAC_HUMAN]] Methylmalonic acidemia with homocystinuria, type cblC. The disease is caused by mutations affecting the gene represented in this entry.
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== Function ==
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[[http://www.uniprot.org/uniprot/MMAC_HUMAN MMAC_HUMAN]] May be involved in the binding and intracellular trafficking of cobalamin (vitamin B12).
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Arrowsmith, C H.]]
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[[Category: Arrowsmith, C H]]
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[[Category: Bountra, C.]]
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[[Category: Bountra, C]]
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[[Category: Delft, F von.]]
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[[Category: Delft, F von]]
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[[Category: Edwards, A.]]
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[[Category: Edwards, A]]
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[[Category: Froese, D S.]]
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[[Category: Froese, D S]]
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[[Category: Gileadi, C.]]
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[[Category: Gileadi, C]]
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[[Category: Gravel, R A.]]
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[[Category: Gravel, R A]]
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[[Category: Krojer, T.]]
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[[Category: Krojer, T]]
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[[Category: Muniz, J R.]]
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[[Category: Muniz, J R]]
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[[Category: Oppermann, U.]]
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[[Category: Oppermann, U]]
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[[Category: SGC, Structural Genomics Consortium.]]
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[[Category: Structural genomic]]
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[[Category: Vollmar, M.]]
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[[Category: Vollmar, M]]
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[[Category: Weigelt, J.]]
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[[Category: Weigelt, J]]
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[[Category: Yue, W W.]]
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[[Category: Yue, W W]]
[[Category: Cblc]]
[[Category: Cblc]]
[[Category: Cobalamin]]
[[Category: Cobalamin]]
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[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]
[[Category: Sgc]]
[[Category: Sgc]]
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[[Category: Structural genomic]]
 
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[[Category: Structural genomics consortium]]
 
[[Category: Vitamin b12]]
[[Category: Vitamin b12]]

Revision as of 13:09, 9 December 2014

crystal structure of human MMACHC

3som, resolution 2.40Å

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