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3nls

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[[Image:3nls.png|left|200px]]
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==Crystal Structure of HIV-1 Protease in Complex with KNI-10772==
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<StructureSection load='3nls' size='340' side='right' caption='[[3nls]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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{{STRUCTURE_3nls| PDB=3nls | SCENE= }}
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3nls]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_type_1_(bru_isolate) Human immunodeficiency virus type 1 (bru isolate)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NLS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NLS FirstGlance]. <br>
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===Crystal Structure of HIV-1 Protease in Complex with KNI-10772===
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=016:(4R)-3-[(2R,3S)-3-{[(2,6-DIMETHYLPHENOXY)ACETYL]AMINO}-2-HYDROXY-4-PHENYLBUTANOYL]-N-[(1S,2R)-2-HYDROXY-2,3-DIHYDRO-1H-INDEN-1-YL]-5,5-DIMETHYL-1,3-THIAZOLIDINE-4-CARBOXAMIDE'>016</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=URE:UREA'>URE</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3kdd|3kdd]], [[3kdc|3kdc]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11686 Human immunodeficiency virus type 1 (BRU ISOLATE)])</td></tr>
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==About this Structure==
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] </span></td></tr>
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[[3nls]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NLS OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nls FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nls OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nls RCSB], [http://www.ebi.ac.uk/pdbsum/3nls PDBsum]</span></td></tr>
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</table>
==See Also==
==See Also==
*[[Virus protease|Virus protease]]
*[[Virus protease|Virus protease]]
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__TOC__
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</StructureSection>
[[Category: HIV-1 retropepsin]]
[[Category: HIV-1 retropepsin]]
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[[Category: Human immunodeficiency virus 1]]
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[[Category: Amzel, L M]]
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[[Category: Amzel, L M.]]
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[[Category: Freire, E]]
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[[Category: Freire, E.]]
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[[Category: Gabelli, S B]]
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[[Category: Gabelli, S B.]]
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[[Category: Kawasaki, Y]]
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[[Category: Kawasaki, Y.]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Protease]]
[[Category: Protease]]

Revision as of 13:42, 9 December 2014

Crystal Structure of HIV-1 Protease in Complex with KNI-10772

3nls, resolution 1.70Å

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