3oy4

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[[Image:3oy4.png|left|200px]]
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==Crystal Structure of HIV-1 L76V Protease in Complex with the Protease Inhibitor Darunavir.==
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<StructureSection load='3oy4' size='340' side='right' caption='[[3oy4]], [[Resolution|resolution]] 1.76&Aring;' scene=''>
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{{STRUCTURE_3oy4| PDB=3oy4 | SCENE= }}
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3oy4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OY4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3OY4 FirstGlance]. <br>
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===Crystal Structure of HIV-1 L76V Protease in Complex with the Protease Inhibitor Darunavir.===
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=017:(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE'>017</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3oxv|3oxv]], [[3oxw|3oxw]], [[3oxx|3oxx]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gag-pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 Human immunodeficiency virus 1])</td></tr>
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==About this Structure==
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] </span></td></tr>
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[[3oy4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OY4 OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3oy4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3oy4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3oy4 RCSB], [http://www.ebi.ac.uk/pdbsum/3oy4 PDBsum]</span></td></tr>
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</table>
==See Also==
==See Also==
*[[Virus protease|Virus protease]]
*[[Virus protease|Virus protease]]
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__TOC__
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</StructureSection>
[[Category: HIV-1 retropepsin]]
[[Category: HIV-1 retropepsin]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
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[[Category: Bandaranayake, R M.]]
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[[Category: Bandaranayake, R M]]
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[[Category: Nalivaika, E A.]]
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[[Category: Nalivaika, E A]]
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[[Category: Schiffer, C A.]]
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[[Category: Schiffer, C A]]
[[Category: Aid]]
[[Category: Aid]]
[[Category: Aspartyl protease]]
[[Category: Aspartyl protease]]

Revision as of 13:47, 9 December 2014

Crystal Structure of HIV-1 L76V Protease in Complex with the Protease Inhibitor Darunavir.

3oy4, resolution 1.76Å

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