3u4m
From Proteopedia
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| - | [[ | + | ==Crystal structure of ribosomal protein tthl1 in complex with 80nt 23s rna from thermus thermophilus== |
| + | <StructureSection load='3u4m' size='340' side='right' caption='[[3u4m]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3u4m]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U4M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3U4M FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1u63|1u63]], [[2vpl|2vpl]], [[2hw8|2hw8]], [[1zho|1zho]], [[1mzp|1mzp]], [[3u42|3u42]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rplA, rpl1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=274 Thermus thermophilus])</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3u4m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u4m OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3u4m RCSB], [http://www.ebi.ac.uk/pdbsum/3u4m PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | The crystal structure of the isolated full-length ribosomal L1 stalk, consisting of Thermus thermophilus ribosomal protein L1 in complex with a specific 80-nucleotide fragment of 23S rRNA, has been solved for the first time at high resolution. The structure revealed details of protein-RNA interactions in the L1 stalk. Analysis of the crystal packing enabled the identification of sticky sites on the protein and the 23S rRNA which may be important for ribosome assembly and function. The structure was used to model different conformational states of the ribosome. This approach provides an insight into the roles of domain II of L1 and helix 78 of rRNA in ribosome function. | ||
| - | + | High-resolution crystal structure of the isolated ribosomal L1 stalk.,Tishchenko S, Gabdulkhakov A, Nevskaya N, Sarskikh A, Kostareva O, Nikonova E, Sycheva A, Moshkovskii S, Garber M, Nikonov S Acta Crystallogr D Biol Crystallogr. 2012 Aug;68(Pt 8):1051-7. Epub 2012 Jul 17. PMID:22868771<ref>PMID:22868771</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| + | </div> | ||
| - | + | ==See Also== | |
| - | + | *[[Ribosomal protein L1|Ribosomal protein L1]] | |
| - | == | + | == References == |
| - | [[ | + | <references/> |
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Thermus thermophilus]] | [[Category: Thermus thermophilus]] | ||
| - | [[Category: Gabdulkhakov, A G | + | [[Category: Gabdulkhakov, A G]] |
| - | [[Category: NIkonov, S V | + | [[Category: NIkonov, S V]] |
| - | [[Category: Nevskaya, N A | + | [[Category: Nevskaya, N A]] |
[[Category: Ribosomal protein]] | [[Category: Ribosomal protein]] | ||
[[Category: Ribosome]] | [[Category: Ribosome]] | ||
Revision as of 14:36, 9 December 2014
Crystal structure of ribosomal protein tthl1 in complex with 80nt 23s rna from thermus thermophilus
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