3vf7
From Proteopedia
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| - | [[ | + | ==Crystal Structure of HIV-1 Protease Mutant L76V with novel P1'-Ligands GRL-02031== |
| + | <StructureSection load='3vf7' size='340' side='right' caption='[[3vf7]], [[Resolution|resolution]] 1.30Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3vf7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_type_1_(bru_isolate) Human immunodeficiency virus type 1 (bru isolate)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VF7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3VF7 FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=031:(3AS,5R,6AR)-HEXAHYDRO-2H-CYCLOPENTA[B]FURAN-5-YL+[(1S,2R)-1-BENZYL-2-HYDROXY-3-([(4-METHOXYPHENYL)SULFONYL]{[(2R)-5-OXOPYRROLIDIN-2-YL]METHYL}AMINO)PROPYL]CARBAMATE'>031</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | ||
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3h5b|3h5b]], [[3vf5|3vf5]], [[3vfa|3vfa]], [[3vfb|3vfb]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gag-pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11686 Human immunodeficiency virus type 1 (BRU ISOLATE)])</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vf7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vf7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3vf7 RCSB], [http://www.ebi.ac.uk/pdbsum/3vf7 PDBsum]</span></td></tr> | ||
| + | </table> | ||
| - | + | ==See Also== | |
| - | + | *[[Virus protease|Virus protease]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
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| - | [[ | + | |
[[Category: HIV-1 retropepsin]] | [[Category: HIV-1 retropepsin]] | ||
| - | [[Category: Chang, Y C.E | + | [[Category: Chang, Y C.E]] |
| - | [[Category: Wang, Y F | + | [[Category: Wang, Y F]] |
| - | [[Category: Weber, I T | + | [[Category: Weber, I T]] |
| - | [[Category: Yu, X X | + | [[Category: Yu, X X]] |
[[Category: Hydrolase-hydrolase inhibitor complex]] | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
[[Category: P1'-ligand]] | [[Category: P1'-ligand]] | ||
[[Category: Protease inhibitor]] | [[Category: Protease inhibitor]] | ||
Revision as of 15:20, 9 December 2014
Crystal Structure of HIV-1 Protease Mutant L76V with novel P1'-Ligands GRL-02031
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