4don
From Proteopedia
(Difference between revisions)
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| - | + | ==Brd4 Bromodomain 1 complex with a fragment 3,4-Dihydro-3-methyl-2(1H)-quinazolinon== | |
| - | + | <StructureSection load='4don' size='340' side='right' caption='[[4don]], [[Resolution|resolution]] 1.52Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4don]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DON OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DON FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3PF:3-METHYL-3,4-DIHYDROQUINAZOLIN-2(1H)-ONE'>3PF</scene></td></tr> | |
| - | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BRD4, HUNK1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4don FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4don OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4don RCSB], [http://www.ebi.ac.uk/pdbsum/4don PDBsum]</span></td></tr> | |
| - | == | + | </table> |
| - | [[4don]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DON OCA]. | + | == Disease == |
| + | [[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity). | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Cao, D Y | + | [[Category: Cao, D Y]] |
| - | [[Category: Chen, T T | + | [[Category: Chen, T T]] |
| - | [[Category: Chen, W Y | + | [[Category: Chen, W Y]] |
| - | [[Category: Shen, J K | + | [[Category: Shen, J K]] |
| - | [[Category: Xiong, B | + | [[Category: Xiong, B]] |
| - | [[Category: Xu, Y C | + | [[Category: Xu, Y C]] |
[[Category: Brd4]] | [[Category: Brd4]] | ||
[[Category: Bromodomain]] | [[Category: Bromodomain]] | ||
[[Category: Four alpha helice]] | [[Category: Four alpha helice]] | ||
[[Category: Signaling protein]] | [[Category: Signaling protein]] | ||
Revision as of 15:30, 9 December 2014
Brd4 Bromodomain 1 complex with a fragment 3,4-Dihydro-3-methyl-2(1H)-quinazolinon
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Categories: Homo sapiens | Cao, D Y | Chen, T T | Chen, W Y | Shen, J K | Xiong, B | Xu, Y C | Brd4 | Bromodomain | Four alpha helice | Signaling protein
