3u39
From Proteopedia
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| - | [[ | + | ==Crystal Stucture of the apo Bacillus Stearothermophilus phosphofructokinase== |
| + | <StructureSection load='3u39' size='340' side='right' caption='[[3u39]], [[Resolution|resolution]] 2.79Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3u39]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U39 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3U39 FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pfkA, pfk ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1422 Geobacillus stearothermophilus])</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/6-phosphofructokinase 6-phosphofructokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.11 2.7.1.11] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3u39 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u39 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3u39 RCSB], [http://www.ebi.ac.uk/pdbsum/3u39 PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | The crystal structure of the unliganded form of Bacillus stearothermophilus phosphofructokinase (BsPFK) was determined using molecular replacement to 2.8 A resolution (Protein Data Bank entry 3U39 ). The apo BsPFK structure serves as the basis for the interpretation of any structural changes seen in the binary or ternary complexes. When the apo BsPFK structure is compared with the previously published liganded structures of BsPFK, the structural impact that the binding of the ligands produces is revealed. This comparison shows that the apo form of BsPFK resembles the substrate-bound form of BsPFK, a finding that differs from previous predictions. | ||
| - | + | Structure of the apo form of Bacillus stearothermophilus phosphofructokinase.,Mosser R, Reddy MC, Bruning JB, Sacchettini JC, Reinhart GD Biochemistry. 2012 Jan 24;51(3):769-75. Epub 2012 Jan 11. PMID:22212099<ref>PMID:22212099</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
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==See Also== | ==See Also== | ||
*[[Phosphofructokinase (PFK)|Phosphofructokinase (PFK)]] | *[[Phosphofructokinase (PFK)|Phosphofructokinase (PFK)]] | ||
| - | + | == References == | |
| - | == | + | <references/> |
| - | < | + | __TOC__ |
| + | </StructureSection> | ||
[[Category: 6-phosphofructokinase]] | [[Category: 6-phosphofructokinase]] | ||
[[Category: Geobacillus stearothermophilus]] | [[Category: Geobacillus stearothermophilus]] | ||
| - | [[Category: Bruning, J B | + | [[Category: Bruning, J B]] |
| - | [[Category: Mosser, R | + | [[Category: Mosser, R]] |
| - | [[Category: Reddy, M C.M | + | [[Category: Reddy, M C.M]] |
| - | [[Category: Reinhart, G D | + | [[Category: Reinhart, G D]] |
| - | [[Category: Sacchettini, J C | + | [[Category: Sacchettini, J C]] |
[[Category: Pfk]] | [[Category: Pfk]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 15:31, 9 December 2014
Crystal Stucture of the apo Bacillus Stearothermophilus phosphofructokinase
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