3vw6

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[[Image:3vw6.jpg|left|200px]]
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==Crystal structure of human apoptosis signal-regulating kinase 1 (ASK1) with imidazopyridine inhibitor==
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<StructureSection load='3vw6' size='340' side='right' caption='[[3vw6]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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{{STRUCTURE_3vw6| PDB=3vw6 | SCENE= }}
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3vw6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VW6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3VW6 FirstGlance]. <br>
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===Crystal structure of human apoptosis signal-regulating kinase 1 (ASK1) with imidazopyridine inhibitor===
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IM6:4-TERT-BUTYL-N-[6-(1H-IMIDAZOL-1-YL)IMIDAZO[1,2-A]PYRIDIN-2-YL]BENZAMIDE'>IM6</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MAP3K5, ASK1, MAPKKK5, MEKK5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mitogen-activated_protein_kinase_kinase_kinase Mitogen-activated protein kinase kinase kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.25 2.7.11.25] </span></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vw6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vw6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3vw6 RCSB], [http://www.ebi.ac.uk/pdbsum/3vw6 PDBsum]</span></td></tr>
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[[3vw6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VW6 OCA].
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</table>
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[[Category: Homo sapiens]]
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__TOC__
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</StructureSection>
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[[Category: Human]]
[[Category: Mitogen-activated protein kinase kinase kinase]]
[[Category: Mitogen-activated protein kinase kinase kinase]]
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[[Category: Fujitani, Y.]]
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[[Category: Fujitani, Y]]
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[[Category: Inoue, Y.]]
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[[Category: Inoue, Y]]
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[[Category: Kawamoto, T.]]
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[[Category: Kawamoto, T]]
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[[Category: Nakagawa, H.]]
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[[Category: Nakagawa, H]]
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[[Category: Okada, K.]]
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[[Category: Okada, K]]
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[[Category: Suzuki, H.]]
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[[Category: Suzuki, H]]
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[[Category: Takekawa, S.]]
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[[Category: Takekawa, S]]
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[[Category: Terao, Y.]]
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[[Category: Terao, Y]]
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[[Category: Uchikawa, O.]]
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[[Category: Uchikawa, O]]
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[[Category: Yamamoto, Y.]]
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[[Category: Yamamoto, Y]]
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[[Category: Yao, S.]]
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[[Category: Yao, S]]
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[[Category: Yashiro, H.]]
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[[Category: Yashiro, H]]
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[[Category: Yoshikawa, M.]]
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[[Category: Yoshikawa, M]]
[[Category: Transferase]]
[[Category: Transferase]]
[[Category: Transferase-transferase inhibitor complex]]
[[Category: Transferase-transferase inhibitor complex]]

Revision as of 15:38, 9 December 2014

Crystal structure of human apoptosis signal-regulating kinase 1 (ASK1) with imidazopyridine inhibitor

3vw6, resolution 2.40Å

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