3uqw
From Proteopedia
(Difference between revisions)
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| - | [[ | + | ==Crystal structure of BACE1 with its inhibitor== |
| + | <StructureSection load='3uqw' size='340' side='right' caption='[[3uqw]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3uqw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UQW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3UQW FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZPY:ETHYL+1-{(2S,3S)-3-[(3-{[(1R)-1-(4-FLUOROPHENYL)ETHYL]CARBAMOYL}-5-[METHYL(METHYLSULFONYL)AMINO]BENZOYL)AMINO]-2-HYDROXY-4-PHENYLBUTYL}-1H-PYRAZOLE-4-CARBOXYLATE'>ZPY</scene></td></tr> | ||
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3uqp|3uqp]], [[4dv9|4dv9]], [[3uqr|3uqr]], [[4dvf|4dvf]], [[3uqu|3uqu]], [[3uqx|3uqx]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BACE1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Memapsin_2 Memapsin 2], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.46 3.4.23.46] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3uqw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uqw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3uqw RCSB], [http://www.ebi.ac.uk/pdbsum/3uqw PDBsum]</span></td></tr> | ||
| + | </table> | ||
| - | + | ==See Also== | |
| - | + | *[[Beta secretase|Beta secretase]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | ||
| - | + | ||
| - | [[ | + | |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Memapsin 2]] | [[Category: Memapsin 2]] | ||
| - | [[Category: Chen, T T | + | [[Category: Chen, T T]] |
| - | [[Category: Chen, W Y | + | [[Category: Chen, W Y]] |
| - | [[Category: Xu, Y C | + | [[Category: Xu, Y C]] |
[[Category: Bace1]] | [[Category: Bace1]] | ||
[[Category: Beta-secretase]] | [[Category: Beta-secretase]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Hydrolase-hydrolase inhibitor complex]] | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
| - | [[Category: Memapsin 2]] | ||
Revision as of 16:52, 9 December 2014
Crystal structure of BACE1 with its inhibitor
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