4eb4

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[[Image:4eb4.png|left|200px]]
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==Crystal structure of mouse thymidylate synthase in ternary complex with dUMP and Tomudex==
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<StructureSection load='4eb4' size='340' side='right' caption='[[4eb4]], [[Resolution|resolution]] 1.74&Aring;' scene=''>
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{{STRUCTURE_4eb4| PDB=4eb4 | SCENE= }}
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4eb4]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EB4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EB4 FirstGlance]. <br>
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===Crystal structure of mouse thymidylate synthase in ternary complex with dUMP and Tomudex===
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=D16:TOMUDEX'>D16</scene>, <scene name='pdbligand=DTT:2,3-DIHYDROXY-1,4-DITHIOBUTANE'>DTT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UMP:2-DEOXYURIDINE+5-MONOPHOSPHATE'>UMP</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Tyms ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thymidylate_synthase Thymidylate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.45 2.1.1.45] </span></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4eb4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eb4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4eb4 RCSB], [http://www.ebi.ac.uk/pdbsum/4eb4 PDBsum]</span></td></tr>
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[[4eb4]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EB4 OCA].
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</table>
==See Also==
==See Also==
*[[Thymidylate synthase|Thymidylate synthase]]
*[[Thymidylate synthase|Thymidylate synthase]]
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__TOC__
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</StructureSection>
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Thymidylate synthase]]
[[Category: Thymidylate synthase]]
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[[Category: Dowiercial, A.]]
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[[Category: Dowiercial, A]]
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[[Category: Jarmula, A.]]
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[[Category: Jarmula, A]]
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[[Category: Rode, W.]]
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[[Category: Rode, W]]
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[[Category: Rypniewski, W R.]]
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[[Category: Rypniewski, W R]]
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[[Category: Wilk, P.]]
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[[Category: Wilk, P]]
[[Category: Methyltransferase]]
[[Category: Methyltransferase]]
[[Category: Nucleotide biosynthesis]]
[[Category: Nucleotide biosynthesis]]
[[Category: Ternary complex]]
[[Category: Ternary complex]]
[[Category: Transferase]]
[[Category: Transferase]]

Revision as of 17:02, 9 December 2014

Crystal structure of mouse thymidylate synthase in ternary complex with dUMP and Tomudex

4eb4, resolution 1.74Å

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