3uw0
From Proteopedia
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| - | [[ | + | ==Pectin methylesterase from Yersinia enterocolitica== |
| + | <StructureSection load='3uw0' size='340' side='right' caption='[[3uw0]], [[Resolution|resolution]] 3.50Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3uw0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Yersinia_enterocolitica_subsp._enterocolitica Yersinia enterocolitica subsp. enterocolitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UW0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3UW0 FirstGlance]. <br> | ||
| + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">YE0549 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=150052 Yersinia enterocolitica subsp. enterocolitica])</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pectinesterase Pectinesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.11 3.1.1.11] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3uw0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uw0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3uw0 RCSB], [http://www.ebi.ac.uk/pdbsum/3uw0 PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Pectin methylesterases (PMEs) are family 8 carbohydrate esterases (CE8s) which remove the methyl group from methylesterified galacturonic acid (GalA) residues within pectin. Although the role of pectinases such as PMEs within dedicated phytopathogens has been well established, the significance of homologous enzymes found within the genomes of human enteropathogens remains to be determined. Presented here is the low-resolution (3.5 A) structure of the CE8 from Yersinia enterocolitica (YeCE8). The high degree of structural conservation in the topology of the active-site cleft and catalytic apparatus that is shared with a characterized PME from a bacterial phytopathogen (i) indicates that YeCE8 is active on methylated pectin and (ii) highlights a more prominent role for pectin utilization in Yersinia than in other enteropathogenic species. | ||
| - | + | Structure of a pectin methylesterase from Yersinia enterocolitica.,Boraston AB, Abbott DW Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Feb 1;68(Pt 2):129-33., Epub 2012 Jan 21. PMID:22297983<ref>PMID:22297983</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
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==See Also== | ==See Also== | ||
*[[Methylesterase|Methylesterase]] | *[[Methylesterase|Methylesterase]] | ||
| - | + | == References == | |
| - | == | + | <references/> |
| - | < | + | __TOC__ |
| + | </StructureSection> | ||
[[Category: Pectinesterase]] | [[Category: Pectinesterase]] | ||
[[Category: Yersinia enterocolitica subsp. enterocolitica]] | [[Category: Yersinia enterocolitica subsp. enterocolitica]] | ||
| - | [[Category: Abbott, D W | + | [[Category: Abbott, D W]] |
| - | [[Category: Boraston, A B | + | [[Category: Boraston, A B]] |
[[Category: Carbohydrate esterase]] | [[Category: Carbohydrate esterase]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Right-handed beta-helix]] | [[Category: Right-handed beta-helix]] | ||
Revision as of 17:08, 9 December 2014
Pectin methylesterase from Yersinia enterocolitica
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