SAM-dependent methyltransferase
From Proteopedia
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| + | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
| - | + | *SAM-dependent O-methyltransferase | |
| - | [[1o54]] – TmSDM – ''Thermotoga maritima''<br /> | + | **[[1o54]] – TmSDM – ''Thermotoga maritima''<br /> |
| - | [[2hnk]] – SDM – ''Leptospira interrogans''<br /> | + | **[[2hnk]] – SDM – ''Leptospira interrogans''<br /> |
| - | [[3r3h]] – SDM – ''Legionella pneumophila'' | + | **[[3r3h]] – SDM – ''Legionella pneumophila'' |
| - | + | *SAM-dependent N-methyltransferase | |
| - | [[1vlm]] – TmSDM (mutant) | + | **[[1vlm]] – TmSDM (mutant) |
| - | + | *SAM-dependent methyltransferase | |
| - | [[1wzn]] – SDM – ''Pyrococcus horikoshii''<br /> | + | **[[1wzn]] – SDM – ''Pyrococcus horikoshii''<br /> |
| - | [[2igt]] – SDM –'' Agrobacterium tumefaciens''<br /> | + | **[[2igt]] – SDM –'' Agrobacterium tumefaciens''<br /> |
| - | [[3cgg]] – CgSDM – ''Corynebacterium glutamicum''<br /> | + | **[[3cgg]] – CgSDM – ''Corynebacterium glutamicum''<br /> |
| - | [[3d2l]] - SDM – ''Exiguobacterium sibiricum''<br /> | + | **[[3d2l]] - SDM – ''Exiguobacterium sibiricum''<br /> |
| - | [[3dh0]] - SDM – ''Aquifex aeolicus''<br /> | + | **[[3dh0]] - SDM – ''Aquifex aeolicus''<br /> |
| - | [[3dp7]] - SDM – ''Bacterioides vulgatus''<br /> | + | **[[3dp7]] - SDM – ''Bacterioides vulgatus''<br /> |
| - | [[3ggd]] - SDM – ''Anabaena variabilis''<br /> | + | **[[3ggd]] - SDM – ''Anabaena variabilis''<br /> |
| - | [[3sm3]] - SDM (mutant) – ''Methanosarcina mazei''<br /> | + | **[[3sm3]] - SDM (mutant) – ''Methanosarcina mazei''<br /> |
| - | [[3bkx]] – SDM – ''Lactobacillus casei''<br /> | + | **[[3bkx]] – SDM – ''Lactobacillus casei''<br /> |
| - | [[3kr9]] – SpSDM – ''Streptococcus pneumonia''<br /> | + | **[[3kr9]] – SpSDM – ''Streptococcus pneumonia''<br /> |
| - | [[3ku1]] – SpSDM + SAM<br /> | + | **[[3ku1]] – SpSDM + SAM<br /> |
| - | [[3lga]] – PaSDM + SAH – ''Pyrococcus abyssi''<br /> | + | **[[3lga]] – PaSDM + SAH – ''Pyrococcus abyssi''<br /> |
| - | [[3mb5]] – PaSDM + SAM<br /> | + | **[[3mb5]] – PaSDM + SAM<br /> |
| - | [[3ou2]] – SlSDM + SAH – ''Streptomyces luridus''<br /> | + | **[[3ou2]] – SlSDM + SAH – ''Streptomyces luridus''<br /> |
| - | [[3ou6]] – SlSDM + SAM<br /> | + | **[[3ou6]] – SlSDM + SAM<br /> |
| - | [[3ou7]] – SlSDM + SAM + phosphonic acid derivative<br /> | + | **[[3ou7]] – SlSDM + SAM + phosphonic acid derivative<br /> |
| - | [[3h2b]] – CgSDM + pyrophosphate + SAH<br /> | + | **[[3h2b]] – CgSDM + pyrophosphate + SAH<br /> |
| - | [[1bc5]] – SDM + chemotaxis receptor peptide + SAH - ''Salmonella typhimurium'' | + | **[[1bc5]] – SDM + chemotaxis receptor peptide + SAH - ''Salmonella typhimurium'' |
| + | }} | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 07:19, 10 December 2014
SAM-dependent methyltransferase (SDM) utilizes the methyl donor S-adenosyl-L-methionine (SAM) as a cofactor to methylate proteins, small molecules, lipids and nucleic acids. SAM forms S-adenosyl-L-homocysteine (SAH) upon demethylation. About 120 members of the SDM family have been identified. They differ in their substrate specificity and the atom targeted for methylation (N, O, C, S). The core of the SDM fold contains alternating β strands and α helices. See also Molecular Playground/CheR.
3D structures of SAM-dependent methyltrasferase
Updated on 10-December-2014
