1od5

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1od5.jpg|left|200px]]<br /><applet load="1od5" size="350" color="white" frame="true" align="right" spinBox="true"
+
[[Image:1od5.jpg|left|200px]]
-
caption="1od5, resolution 2.10&Aring;" />
+
 
-
'''CRYSTAL STRUCTURE OF GLYCININ A3B4 SUBUNIT HOMOHEXAMER'''<br />
+
{{Structure
 +
|PDB= 1od5 |SIZE=350|CAPTION= <scene name='initialview01'>1od5</scene>, resolution 2.10&Aring;
 +
|SITE= <scene name='pdbsite=AC1:Mg+Binding+Site+For+Chain+B'>AC1</scene>
 +
|LIGAND= <scene name='pdbligand=CO3:CARBONATE+ION'>CO3</scene> and <scene name='pdbligand=MG:MAGNESIUM ION'>MG</scene>
 +
|ACTIVITY=
 +
|GENE=
 +
}}
 +
 
 +
'''CRYSTAL STRUCTURE OF GLYCININ A3B4 SUBUNIT HOMOHEXAMER'''
 +
 
==Overview==
==Overview==
Line 7: Line 16:
==About this Structure==
==About this Structure==
-
1OD5 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Glycine_max Glycine max] with <scene name='pdbligand=CO3:'>CO3</scene> and <scene name='pdbligand=MG:'>MG</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Known structural/functional Site: <scene name='pdbsite=AC1:Mg+Binding+Site+For+Chain+B'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OD5 OCA].
+
1OD5 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Glycine_max Glycine max]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OD5 OCA].
==Reference==
==Reference==
-
Crystal structure of soybean 11S globulin: glycinin A3B4 homohexamer., Adachi M, Kanamori J, Masuda T, Yagasaki K, Kitamura K, Mikami B, Utsumi S, Proc Natl Acad Sci U S A. 2003 Jun 10;100(12):7395-400. Epub 2003 May 27. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12771376 12771376]
+
Crystal structure of soybean 11S globulin: glycinin A3B4 homohexamer., Adachi M, Kanamori J, Masuda T, Yagasaki K, Kitamura K, Mikami B, Utsumi S, Proc Natl Acad Sci U S A. 2003 Jun 10;100(12):7395-400. Epub 2003 May 27. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12771376 12771376]
[[Category: Glycine max]]
[[Category: Glycine max]]
[[Category: Single protein]]
[[Category: Single protein]]
Line 22: Line 31:
[[Category: CO3]]
[[Category: CO3]]
[[Category: MG]]
[[Category: MG]]
-
[[Category: 11s]]
+
[[Category: 11]]
[[Category: globulin]]
[[Category: globulin]]
[[Category: glycinin]]
[[Category: glycinin]]
Line 28: Line 37:
[[Category: soybean]]
[[Category: soybean]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:16:21 2008''
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:09:10 2008''

Revision as of 11:09, 20 March 2008

Image:1od5.jpg


PDB ID 1od5

Drag the structure with the mouse to rotate
, resolution 2.10Å
Sites:
Ligands: and
Coordinates: save as pdb, mmCIF, xml



CRYSTAL STRUCTURE OF GLYCININ A3B4 SUBUNIT HOMOHEXAMER


Overview

Most plant seeds contain 11S globulins as major storage proteins for their nutrition. Soybean glycinin belongs to the 11S globulin family and consists of five kinds of subunits. We determined the crystal structure of a homohexamer of the glycinin A3B4 subunit at 2.1-A resolution. The crystal structure shows that the hexamer has 32-point group symmetry formed by face-to-face stacking of two trimers. The interface buries the highly conserved interchain disulfide. Based on the structure, we propose that an ingenious face-to-face mechanism controls the hexamer formation of the 11S globulin by movement of a mobile disordered region to the side of the trimer after posttranslational processing. Electrostatic analysis of the faces suggests that the interchain disulfide-containing face has high positive potential at acidic pH, which induces dissociation of the hexamer into trimers that may be susceptible to proteinases after seed imbibition. This dissociation might result in the degradation and mobilization of 11S globulins as storage proteins in embryos during germination and seedling growth.

About this Structure

1OD5 is a Single protein structure of sequence from Glycine max. Full crystallographic information is available from OCA.

Reference

Crystal structure of soybean 11S globulin: glycinin A3B4 homohexamer., Adachi M, Kanamori J, Masuda T, Yagasaki K, Kitamura K, Mikami B, Utsumi S, Proc Natl Acad Sci U S A. 2003 Jun 10;100(12):7395-400. Epub 2003 May 27. PMID:12771376

Page seeded by OCA on Thu Mar 20 13:09:10 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1od5"
Personal tools