Shikimate kinase

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{{#tree:id=OrganizedByTopic|openlevels=0|
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===Shikimate kinase===
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*Shikimate kinase
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[[2g1j]], [[2iyt]] – MtSK – ''Mycobacterium tuberculosis''<br />
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**[[2g1j]], [[2iyt]] – MtSK – ''Mycobacterium tuberculosis''<br />
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[[2pt5]] – SK – ''Aquifex aeolicus'' <br />
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**[[2pt5]] – SK – ''Aquifex aeolicus'' <br />
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[[3nwj]] – SK – ''Arabidopsis thaliana''<br />
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**[[3nwj]] – SK – ''Arabidopsis thaliana''<br />
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[[3trf]] – SK – ''Coxiella burnetii''<br />
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**[[3trf]] – SK – ''Coxiella burnetii''<br />
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[[3vaa]] – SK – ''Bacterioides thetaiotaomicron''<br />
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**[[3vaa]] – SK – ''Bacterioides thetaiotaomicron''<br />
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[[1via]] – SK – ''Campylobacter jejuni''<br />
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**[[1via]] – SK – ''Campylobacter jejuni''<br />
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[[1zuh]], [[3hr7]] – HpSK – ''Helicobacter pylori''<br />
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**[[1zuh]], [[3hr7]] – HpSK – ''Helicobacter pylori''<br />
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[[3mrs]] – HpSK (mutant)<br />
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**[[3mrs]] – HpSK (mutant)<br />
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[[1shk]] – EchSK – ''Erwinia chrysanthemi''<br />
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**[[1shk]] – EchSK – ''Erwinia chrysanthemi''<br />
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[[1e6c]] – EchSK (mutant) <br />
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**[[1e6c]] – EchSK (mutant) <br />
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[[1kag]] – SK – ''Escherichia coli''<br />
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**[[1kag]] – SK – ''Escherichia coli''<br />
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===Shikimate kinase binary complex===
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*Shikimate kinase binary complex
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[[1l4u]], [[1l4y]], [[1u8a]], [[2iyu]], [[2iyv]], [[2dft]] – MtSK + ADP <br />
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**[[1l4u]], [[1l4y]], [[1u8a]], [[2iyu]], [[2iyv]], [[2dft]] – MtSK + ADP <br />
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[[2iyw]] – MtSK + ATP <br />
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**[[2iyw]] – MtSK + ATP <br />
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[[3baf]] – MtSK + AMPPNP <br />
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**[[3baf]] – MtSK + AMPPNP <br />
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[[2shk]] – EchSK + ADP <br />
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**[[2shk]] – EchSK + ADP <br />
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[[1zui]] – HpSK + shikimate<br />
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**[[1zui]] – HpSK + shikimate<br />
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[[3n2e]] – HpSK (mutant) + inhibitor<br />
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**[[3n2e]] – HpSK (mutant) + inhibitor<br />
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[[2g1k]], [[2iyr]], [[2iys]], [[2iyx]] – MtSK + shikimate<br />
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**[[2g1k]], [[2iyr]], [[2iys]], [[2iyx]] – MtSK + shikimate<br />
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[[2iyy]] – MtSK + shikimate-3-phosphate<br />
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**[[2iyy]] – MtSK + shikimate-3-phosphate<br />
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===Shikimate kinase ternary complex===
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*Shikimate kinase ternary complex
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[[2iyz]] – MtSK + ADP + shikimate-3-phosphate<br />
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[[1we2]], [[2dfn]], [[2iyq]] – MtSK + ADP + shikimate<br />
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[[1zyu]] – MtSK + AMPPCP + shikimate<br />
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[[3muf]] – HpSK + ADP + shikimate-3-phosphate<br />
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**[[2iyz]] – MtSK + ADP + shikimate-3-phosphate<br />
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**[[1we2]], [[2dfn]], [[2iyq]] – MtSK + ADP + shikimate<br />
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**[[1zyu]] – MtSK + AMPPCP + shikimate<br />
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**[[3muf]] – HpSK + ADP + shikimate-3-phosphate<br />
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}}
[[Category: Topic Page]]
[[Category: Topic Page]]

Revision as of 10:15, 10 December 2014

Template:STRUCTURE 2dfn

Shikimate kinase (SK) catalyzes the ATP-dependent phosphorylation of shikimate to produce shikimate 3-phosphate. It is part of the plant and bacteria pathway of synthesizing aromatic acids. SK inhibitors can be used as antimicrobial drugs.

3D Structures of shikimate kinase

Updated on 10-December-2014

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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