1on4
From Proteopedia
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| - | [[Image:1on4.jpg|left|200px]] | + | [[Image:1on4.jpg|left|200px]] |
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| - | '''Solution structure of soluble domain of Sco1 from Bacillus Subtilis''' | + | {{Structure |
| + | |PDB= 1on4 |SIZE=350|CAPTION= <scene name='initialview01'>1on4</scene> | ||
| + | |SITE= | ||
| + | |LIGAND= | ||
| + | |ACTIVITY= | ||
| + | |GENE= YPMQ ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 Bacillus subtilis]) | ||
| + | }} | ||
| + | |||
| + | '''Solution structure of soluble domain of Sco1 from Bacillus Subtilis''' | ||
| + | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1ON4 is a [ | + | 1ON4 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ON4 OCA]. |
==Reference== | ==Reference== | ||
| - | Solution structure of Sco1: a thioredoxin-like protein Involved in cytochrome c oxidase assembly., Balatri E, Banci L, Bertini I, Cantini F, Ciofi-Baffoni S, Structure. 2003 Nov;11(11):1431-43. PMID:[http:// | + | Solution structure of Sco1: a thioredoxin-like protein Involved in cytochrome c oxidase assembly., Balatri E, Banci L, Bertini I, Cantini F, Ciofi-Baffoni S, Structure. 2003 Nov;11(11):1431-43. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14604533 14604533] |
[[Category: Bacillus subtilis]] | [[Category: Bacillus subtilis]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: cox assembly protein]] | [[Category: cox assembly protein]] | ||
[[Category: nmr structure]] | [[Category: nmr structure]] | ||
| - | [[Category: sco1 from b. | + | [[Category: sco1 from b. subtili]] |
[[Category: spine]] | [[Category: spine]] | ||
| - | [[Category: structural | + | [[Category: structural genomic]] |
[[Category: structural proteomics in europe]] | [[Category: structural proteomics in europe]] | ||
[[Category: thioredoxin-like fold]] | [[Category: thioredoxin-like fold]] | ||
[[Category: ypmq]] | [[Category: ypmq]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:13:02 2008'' |
Revision as of 11:13, 20 March 2008
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| Gene: | YPMQ (Bacillus subtilis) | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Solution structure of soluble domain of Sco1 from Bacillus Subtilis
Overview
Sco1, a protein required for the proper assembly of cytochrome c oxidase, has a soluble domain anchored to the cytoplasmic membrane through a single transmembrane segment. The solution structure of the soluble part of apoSco1 from Bacillus subtilis has been solved by NMR and the internal mobility characterized. Its fold places Sco1 in a distinct subgroup of the functionally unrelated thioredoxin proteins. In vitro Sco1 binds copper(I) through a CXXXCP motif and possibly His 135 and copper(II) in two different species, thus suggesting that copper(II) is adventitious more than physiological. The Sco1 structure represents the first structure of this class of proteins, present in a variety of eukaryotic and bacterial organisms, and elucidates a link between copper trafficking proteins and thioredoxins. The availability of the structure has allowed us to model the homologs Sco1 and Sco2 from S. cerevisiae and to discuss the physiological role of the Sco family.
About this Structure
1ON4 is a Single protein structure of sequence from Bacillus subtilis. Full crystallographic information is available from OCA.
Reference
Solution structure of Sco1: a thioredoxin-like protein Involved in cytochrome c oxidase assembly., Balatri E, Banci L, Bertini I, Cantini F, Ciofi-Baffoni S, Structure. 2003 Nov;11(11):1431-43. PMID:14604533
Page seeded by OCA on Thu Mar 20 13:13:02 2008
Categories: Bacillus subtilis | Single protein | Balatri, E. | Banci, L. | Bertini, I. | Cantini, F. | Ciofi-Baffoni, S. | SPINE, Structural Proteomics in Europe. | Copper protein | Cox assembly protein | Nmr structure | Sco1 from b. subtili | Spine | Structural genomic | Structural proteomics in europe | Thioredoxin-like fold | Ypmq
