4rur

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m (Protected "4rur" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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==Yeast 20S proteasome in complex with the alkaloid indolo-phakellin (4)==
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<StructureSection load='4rur' size='340' side='right' caption='[[4rur]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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The entry 4rur is ON HOLD
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4rur]] is a 28 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] and [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RUR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RUR FirstGlance]. <br>
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Authors: Beck, P., Lansdell, T.A., Hewlett, N.M., Tepe, J.J., Groll, M.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3WE:(2E,3AR,14AS)-9-BROMO-2-IMINO-1,2,3,5,6,14A-HEXAHYDRO-4H,8H-IMIDAZO[4,5 5,6]PYRROLO[1,2 4,5]PYRAZINO[1,2-A]INDOL-8-ONE'>3WE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ryp|1ryp]]</td></tr>
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Description: Yeast 20S proteasome in complex with the alkaloid indolo-phakellin (4)
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Proteasome_endopeptidase_complex Proteasome endopeptidase complex], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.25.1 3.4.25.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rur FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rur OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4rur RCSB], [http://www.ebi.ac.uk/pdbsum/4rur PDBsum]</span></td></tr>
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</table>
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__TOC__
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</StructureSection>
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[[Category: Proteasome endopeptidase complex]]
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[[Category: Saccharomyces cerevisiae]]
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[[Category: Saccharomyces cerevisiae s288c]]
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[[Category: Beck, P]]
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[[Category: Groll, M]]
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[[Category: Hewlett, N M]]
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[[Category: Lansdell, T A]]
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[[Category: Tepe, J J]]
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[[Category: Alkaloid]]
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[[Category: Drug discovery]]
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[[Category: Halogen bonding]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Proteasome]]
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[[Category: Reversible inhibition]]

Revision as of 16:27, 10 December 2014

Yeast 20S proteasome in complex with the alkaloid indolo-phakellin (4)

4rur, resolution 2.50Å

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