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4wab

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'''Unreleased structure'''
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==Crystal structure of mPGES1 solved by native-SAD phasing==
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<StructureSection load='4wab' size='340' side='right' caption='[[4wab]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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The entry 4wab is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4wab]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WAB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WAB FirstGlance]. <br>
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Authors: Weinert, T., Li, D., Howe, N., Caffrey, M., Wang, M.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=LVJ:2-[[2,6-BIS(CHLORANYL)-3-[(2,2-DIMETHYLPROPANOYLAMINO)METHYL]PHENYL]AMINO]-1-METHYL-6-(2-METHYL-2-OXIDANYL-PROPOXY)-N-[2,2,2-TRIS(FLUORANYL)ETHYL]BENZIMIDAZOLE-5-CARBOXAMIDE'>LVJ</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Prostaglandin-E_synthase Prostaglandin-E synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.99.3 5.3.99.3] </span></td></tr>
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Description: Crystal structure of mPGES1 solved by native-SAD phasing
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wab FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wab OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4wab RCSB], [http://www.ebi.ac.uk/pdbsum/4wab PDBsum]</span></td></tr>
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</table>
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__TOC__
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</StructureSection>
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[[Category: Prostaglandin-E synthase]]
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[[Category: Caffrey, M]]
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[[Category: Howe, N]]
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[[Category: Li, D]]
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[[Category: Wang, M]]
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[[Category: Weinert, T]]
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[[Category: Anomalous dispersion]]
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[[Category: Cancer]]
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[[Category: Drug target]]
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[[Category: In meso crystallization]]
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[[Category: Inflammation]]
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[[Category: Inhibitor]]
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[[Category: Isomerase]]
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[[Category: Leukotriene c4 synthase]]
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[[Category: Lipid metabolism]]
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[[Category: Mapag]]
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[[Category: Membrane protein]]
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[[Category: Membrane-associated proteins in eicosanoid and glutathione metabolism]]
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[[Category: Microcrystal]]
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[[Category: Mpges1]]
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[[Category: Native-sad]]
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[[Category: Pain]]
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[[Category: S-sad]]
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[[Category: Sulfur-sad]]

Revision as of 16:29, 10 December 2014

Crystal structure of mPGES1 solved by native-SAD phasing

4wab, resolution 2.70Å

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