4lbd

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[[Image:4lbd.png|left|200px]]
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==LIGAND-BINDING DOMAIN OF THE HUMAN RETINOIC ACID RECEPTOR GAMMA BOUND TO THE SYNTHETIC AGONIST BMS961==
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<StructureSection load='4lbd' size='340' side='right' caption='[[4lbd]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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{{STRUCTURE_4lbd| PDB=4lbd | SCENE= }}
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4lbd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LBD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LBD FirstGlance]. <br>
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===LIGAND-BINDING DOMAIN OF THE HUMAN RETINOIC ACID RECEPTOR GAMMA BOUND TO THE SYNTHETIC AGONIST BMS961===
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=961:3-FLUORO-4-[2-HYDROXY-2-(5,5,8,8-TETRAMETHYL-5,6,7,8,-TETRAHYDRO-NAPHTALEN-2-YL)-ACETYLAMINO]-BENZOIC+ACID'>961</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HRARGAMMA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lbd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lbd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4lbd RCSB], [http://www.ebi.ac.uk/pdbsum/4lbd PDBsum]</span></td></tr>
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==About this Structure==
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</table>
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[[4lbd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LBD OCA].
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lb/4lbd_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
*[[Retinoic acid receptor|Retinoic acid receptor]]
*[[Retinoic acid receptor|Retinoic acid receptor]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:009501913</ref><ref group="xtra">PMID:015048824</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Klaholz, B P.]]
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[[Category: Klaholz, B P]]
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[[Category: Mitschler, A.]]
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[[Category: Mitschler, A]]
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[[Category: Moras, D.]]
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[[Category: Moras, D]]
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[[Category: Renaud, J P.]]
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[[Category: Renaud, J P]]
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[[Category: SPINE, Structural Proteomics in Europe.]]
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[[Category: SPINE, Structural Proteomics in Europe]]
[[Category: Active conformation]]
[[Category: Active conformation]]
[[Category: All-trans retinoic acid]]
[[Category: All-trans retinoic acid]]

Revision as of 16:55, 10 December 2014

LIGAND-BINDING DOMAIN OF THE HUMAN RETINOIC ACID RECEPTOR GAMMA BOUND TO THE SYNTHETIC AGONIST BMS961

4lbd, resolution 2.50Å

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