4lbd
From Proteopedia
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- | + | ==LIGAND-BINDING DOMAIN OF THE HUMAN RETINOIC ACID RECEPTOR GAMMA BOUND TO THE SYNTHETIC AGONIST BMS961== | |
- | + | <StructureSection load='4lbd' size='340' side='right' caption='[[4lbd]], [[Resolution|resolution]] 2.50Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[4lbd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LBD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LBD FirstGlance]. <br> | |
- | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=961:3-FLUORO-4-[2-HYDROXY-2-(5,5,8,8-TETRAMETHYL-5,6,7,8,-TETRAHYDRO-NAPHTALEN-2-YL)-ACETYLAMINO]-BENZOIC+ACID'>961</scene></td></tr> | |
- | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HRARGAMMA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lbd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lbd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4lbd RCSB], [http://www.ebi.ac.uk/pdbsum/4lbd PDBsum]</span></td></tr> | |
- | == | + | </table> |
- | [[4lbd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LBD OCA]. | + | == Evolutionary Conservation == |
+ | [[Image:Consurf_key_small.gif|200px|right]] | ||
+ | Check<jmol> | ||
+ | <jmolCheckbox> | ||
+ | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lb/4lbd_consurf.spt"</scriptWhenChecked> | ||
+ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
+ | <text>to colour the structure by Evolutionary Conservation</text> | ||
+ | </jmolCheckbox> | ||
+ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | ||
+ | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
*[[Retinoic acid receptor|Retinoic acid receptor]] | *[[Retinoic acid receptor|Retinoic acid receptor]] | ||
- | + | __TOC__ | |
- | + | </StructureSection> | |
- | + | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
- | [[Category: Klaholz, B P | + | [[Category: Klaholz, B P]] |
- | [[Category: Mitschler, A | + | [[Category: Mitschler, A]] |
- | [[Category: Moras, D | + | [[Category: Moras, D]] |
- | [[Category: Renaud, J P | + | [[Category: Renaud, J P]] |
- | [[Category: SPINE, Structural Proteomics in Europe | + | [[Category: SPINE, Structural Proteomics in Europe]] |
[[Category: Active conformation]] | [[Category: Active conformation]] | ||
[[Category: All-trans retinoic acid]] | [[Category: All-trans retinoic acid]] |
Revision as of 16:55, 10 December 2014
LIGAND-BINDING DOMAIN OF THE HUMAN RETINOIC ACID RECEPTOR GAMMA BOUND TO THE SYNTHETIC AGONIST BMS961
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Categories: Homo sapiens | Klaholz, B P | Mitschler, A | Moras, D | Renaud, J P | SPINE, Structural Proteomics in Europe | Active conformation | All-trans retinoic acid | Complex | Holo form | Ligand-binding domain | Ligand-dependent | Nuclear receptor | Retinoic acid receptor | Spine | Structural genomic | Structural proteomics in europe | Transcription regulation