This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4lbd
From Proteopedia
(Difference between revisions)
m (Protected "4lbd" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | + | ==LIGAND-BINDING DOMAIN OF THE HUMAN RETINOIC ACID RECEPTOR GAMMA BOUND TO THE SYNTHETIC AGONIST BMS961== | |
| - | + | <StructureSection load='4lbd' size='340' side='right' caption='[[4lbd]], [[Resolution|resolution]] 2.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4lbd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LBD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LBD FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=961:3-FLUORO-4-[2-HYDROXY-2-(5,5,8,8-TETRAMETHYL-5,6,7,8,-TETRAHYDRO-NAPHTALEN-2-YL)-ACETYLAMINO]-BENZOIC+ACID'>961</scene></td></tr> | |
| - | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HRARGAMMA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lbd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lbd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4lbd RCSB], [http://www.ebi.ac.uk/pdbsum/4lbd PDBsum]</span></td></tr> | |
| - | == | + | </table> |
| - | [[4lbd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LBD OCA]. | + | == Evolutionary Conservation == |
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lb/4lbd_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
*[[Retinoic acid receptor|Retinoic acid receptor]] | *[[Retinoic acid receptor|Retinoic acid receptor]] | ||
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Klaholz, B P | + | [[Category: Klaholz, B P]] |
| - | [[Category: Mitschler, A | + | [[Category: Mitschler, A]] |
| - | [[Category: Moras, D | + | [[Category: Moras, D]] |
| - | [[Category: Renaud, J P | + | [[Category: Renaud, J P]] |
| - | [[Category: SPINE, Structural Proteomics in Europe | + | [[Category: SPINE, Structural Proteomics in Europe]] |
[[Category: Active conformation]] | [[Category: Active conformation]] | ||
[[Category: All-trans retinoic acid]] | [[Category: All-trans retinoic acid]] | ||
Revision as of 16:55, 10 December 2014
LIGAND-BINDING DOMAIN OF THE HUMAN RETINOIC ACID RECEPTOR GAMMA BOUND TO THE SYNTHETIC AGONIST BMS961
| |||||||||||
Categories: Homo sapiens | Klaholz, B P | Mitschler, A | Moras, D | Renaud, J P | SPINE, Structural Proteomics in Europe | Active conformation | All-trans retinoic acid | Complex | Holo form | Ligand-binding domain | Ligand-dependent | Nuclear receptor | Retinoic acid receptor | Spine | Structural genomic | Structural proteomics in europe | Transcription regulation
