Thiolase
From Proteopedia
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Two different classes of '''thiolases''' are found . Degrative thiolase like '''3-ketoacyl-CoA thiolase''' (KCT) is involved in fatty acid β oxidation. Biosynthetic thiolases like '''acetoacetyl-CoA thiolase''' (ACT) are involved in the thiolysis of acetoacetyl-CoA. | Two different classes of '''thiolases''' are found . Degrative thiolase like '''3-ketoacyl-CoA thiolase''' (KCT) is involved in fatty acid β oxidation. Biosynthetic thiolases like '''acetoacetyl-CoA thiolase''' (ACT) are involved in the thiolysis of acetoacetyl-CoA. | ||
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For Bacterial Thiolase see [[Bacterial thiolase]] | For Bacterial Thiolase see [[Bacterial thiolase]] | ||
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
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| - | + | *3-ketoacyl-CoA thiolase | |
| - | [[2wu9]], [[2c7y]], [[2c7z]] – KCT peroxisomal residues 36-462 – ''Arabidopsis thaliana''<br /> | + | **[[2wu9]], [[2c7y]], [[2c7z]] – KCT peroxisomal residues 36-462 – ''Arabidopsis thaliana''<br /> |
| - | [[2wua]] - KCT peroxisomal residues 17-449 (mutant) – sunflower<br /> | + | **[[2wua]] - KCT peroxisomal residues 17-449 (mutant) – sunflower<br /> |
| - | [[2iik]] – hKCT peroximal - human<br /> | + | **[[2iik]] – hKCT peroximal - human<br /> |
| - | [[3goa]] – KCT – ''Salmonella typhimurium''<br /> | + | **[[3goa]] – KCT – ''Salmonella typhimurium''<br /> |
| - | [[1afw]], [[1pxt]] – yKCT peroxisomal - yeast<br /> | + | **[[1afw]], [[1pxt]] – yKCT peroxisomal - yeast<br /> |
| - | [[3w15]] - yKCT peroxisomal residues 27-396 + peroxiomal membrane protein PEX21 + peroxisomal targeting signal receptor<br /> | + | **[[3w15]] - yKCT peroxisomal residues 27-396 + peroxiomal membrane protein PEX21 + peroxisomal targeting signal receptor<br /> |
| - | [[2d3t]] – PfKCT + fatty oxidation complex β subunit – ''Pseudomonas fragi''<br /> | + | **[[2d3t]] – PfKCT + fatty oxidation complex β subunit – ''Pseudomonas fragi''<br /> |
| - | [[1wdk]], [[1wdl]], [[1wdm]] - PfKCT + fatty oxidation complex α subunit | + | **[[1wdk]], [[1wdl]], [[1wdm]] - PfKCT + fatty oxidation complex α subunit |
| - | + | *Acetoacetyl-CoA thiolase | |
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| + | **[[1m4s]], [[1m4t]], [[1dlu]], [[1qfl]] - ZrACT – ''Zoogloea ramigera''<br /> | ||
| + | **[[1dm3]], [[1dlv]] – ZrACT + CoA<br /> | ||
| + | **[[2wku]], [[2wl6]], [[1m1t]], [[1m3k]] - ZrACT (mutant) <br /> | ||
| + | **[[2wkt]], [[2wkv]], [[2wl4]], [[2wl5]], [[2vtz]], [[2vu0]], [[1m3z]] – ZrACT (mutant) + CoA<br /> | ||
| + | **[[1m1o]] - ZrACT (mutant) + acetoacetyl-CoA<br /> | ||
| + | **[[2vu0]], [[1nl7]] - ZrACT + CoA<br /> | ||
| + | **[[2vu1]], [[2vu2]], [[1ou6]] - ZrACT + pantheteine-11-pivalate<br /> | ||
| + | **[[2ib7]], [[2ib8]], [[2ib9]], [[2ibu]], [[2ibw]], [[2iby]], [[2f2s]] – hACT mitochondrial<br /> | ||
| + | **[[1wl5]] - hACT cytosolic<br /> | ||
| + | **[[1wl4]] – hACT cytosolic + CoA<br /> | ||
| + | **[[4dd5]], [[4e1l]] – ACT – ''Clostridium difficile''<br /> | ||
| + | }} | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 11:33, 11 December 2014
Two different classes of thiolases are found . Degrative thiolase like 3-ketoacyl-CoA thiolase (KCT) is involved in fatty acid β oxidation. Biosynthetic thiolases like acetoacetyl-CoA thiolase (ACT) are involved in the thiolysis of acetoacetyl-CoA.
For Bacterial Thiolase see Bacterial thiolase
3D Structures of Thiolase
Updated on 11-December-2014
