Major histocompatibility complex
From Proteopedia
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<StructureSection load='2hla' size='400' side='right' caption='Human MHC class I complex (grey) with β 2-microglobulin (green), [[2hla]]' scene=''> | <StructureSection load='2hla' size='400' side='right' caption='Human MHC class I complex (grey) with β 2-microglobulin (green), [[2hla]]' scene=''> | ||
''' Major Histocompatibility Complex''' (MHC) are part of the cell immune system. MHC molecules display antigens on the host cell’s surface. T cell or natural killer receptors recognize the MHC:peptide and activate the immune response.<br /> | ''' Major Histocompatibility Complex''' (MHC) are part of the cell immune system. MHC molecules display antigens on the host cell’s surface. T cell or natural killer receptors recognize the MHC:peptide and activate the immune response.<br /> | ||
| - | * '''MHC class I''' ([[Major Histocompatibility Complex Class I]]) are found in all nucleated cells. These | + | * '''MHC class I''' ([[Major Histocompatibility Complex Class I]]) are found in all nucleated cells. These cell surface proteins display peptides from cellular intrinsic proteins. For more details see <br /> |
*[[Effect of HCMV on Major Histocompatibility Complex Class I]]<br /> | *[[Effect of HCMV on Major Histocompatibility Complex Class I]]<br /> | ||
*[[MR1 Binds Vitamin Metabolites]].<br /> | *[[MR1 Binds Vitamin Metabolites]].<br /> | ||
| - | * '''MHC class II''' are found in professional antigen-presenting cells like macrophages. These | + | * '''MHC class II''' are found in professional antigen-presenting cells like macrophages. These cell surface proteins display peptides from cellular extrinsic proteins. |
</StructureSection> | </StructureSection> | ||
Revision as of 09:35, 15 December 2014
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3D structures of MHC
Updated on 15-December-2014
Proteopedia Page Contributors and Editors (what is this?)
Michal Harel, Joel L. Sussman, Alexander Berchansky, Tihitina Y Aytenfisu, Eric Martz, Sandra B. Gabelli
