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Transcription initiation factor

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* '''TFIID''' recognizes the promoter sequence on the DNA.<br />
* '''TFIID''' recognizes the promoter sequence on the DNA.<br />
* '''TFIIF''' binds RNA polymerase III prohibiting it to bind to DNA outside the promoter.
* '''TFIIF''' binds RNA polymerase III prohibiting it to bind to DNA outside the promoter.
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</StructureSection>
==3D structures of transcription initiation factors==
==3D structures of transcription initiation factors==
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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{{#tree:id=OrganizedByTopic|openlevels=0|
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===TFIIA===
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*TFIIA
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[[1ytf]], [[1nh2]], [[1rm1]] – yTFIIA + TBP + DNA – yeast<br />
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**[[1ytf]], [[1nh2]], [[1rm1]] – yTFIIA + TBP + DNA – yeast<br />
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[[1nvp]] – hTFIIA + TATA-binding protein + DNA – human<br />
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**[[1nvp]] – hTFIIA + TATA-binding protein + DNA – human<br />
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===TFIIB===
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*TFIIB
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[[1pft]] – TFIIB N terminal – ''Pyrococcus furiosus'' – NMR<BR />
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**[[1pft]] – TFIIB N terminal – ''Pyrococcus furiosus'' – NMR<BR />
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[[1tfb]] – hTFIIB - NMR<BR />
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**[[1tfb]] – hTFIIB - NMR<BR />
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[[1dl6]] - hTFIIB N terminal – NMR<br />
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**[[1dl6]] - hTFIIB N terminal – NMR<br />
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[[1rly]] - hTFIIB Zn ribbon domain + Zn – NMR<br />
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**[[1rly]] - hTFIIB Zn ribbon domain + Zn – NMR<br />
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[[1ro4]] - hTFIIB Zn ribbon domain – NMR<br />
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**[[1ro4]] - hTFIIB Zn ribbon domain – NMR<br />
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[[1vol]], [[1c9b]] – hTFIIB + TBP + DNA<BR />
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**[[1vol]], [[1c9b]] – hTFIIB + TBP + DNA<BR />
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[[3k1f]], [[3k7a]], [[4bbr]], [[4bbs]] – yTFIIB + RNA polymerase II<br />
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**[[3k1f]], [[3k7a]], [[4bbr]], [[4bbs]] – yTFIIB + RNA polymerase II<br />
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[[1ais]], [[1d3u]] - TFIIB C terminal + TBP + DNA – ''Pyrococcus woesei''
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**[[1ais]], [[1d3u]] - TFIIB C terminal + TBP + DNA – ''Pyrococcus woesei''
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===TFIID===
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*TFIID
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[[1bh8]] – hTFIID<BR />
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**[[1bh8]] – hTFIID<BR />
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[[1eqf]] – hTFIID subunit 1<br />
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**[[1eqf]] – hTFIID subunit 1<br />
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[[3uv5]], [[3uv4]] – hTFIID subunit 1 bromodomain <br />
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**[[3uv5]], [[3uv4]] – hTFIID subunit 1 bromodomain <br />
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[[3aad]] – hTFIID subunit 1 bromodomain + histone chaperone ASF1A<br />
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**[[3aad]] – hTFIID subunit 1 bromodomain + histone chaperone ASF1A<br />
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[[1tba]] – TFIID – ''Drosophila melanogaster'' - NMR<BR />
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**[[1tba]] – TFIID – ''Drosophila melanogaster'' - NMR<BR />
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[[1bh9]] – hTFIID + PCMBS<BR />
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**[[1bh9]] – hTFIID + PCMBS<BR />
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[[1qn3]], [[1qn4]], [[1qn5]], [[1qn6]], [[1qn7]], [[1qn8]], [[1qn9]], [[1qna]], [[1qnb]], [[1qnc]], [[1qne]] – TFIID + DNA – ''Arabidopsis thaliana''
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**[[1qn3]], [[1qn4]], [[1qn5]], [[1qn6]], [[1qn7]], [[1qn8]], [[1qn9]], [[1qna]], [[1qnb]], [[1qnc]], [[1qne]] – TFIID + DNA – ''Arabidopsis thaliana''
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'''TFIIE'''
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*TFIIE
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[[1vd4]] - hTFIIB Zn finger domain – NMR<br />
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**[[1vd4]] - hTFIIB Zn finger domain – NMR<br />
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[[2rnq]] – hTFIIE C terminal - NMR<br />
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**[[2rnq]] – hTFIIE C terminal - NMR<br />
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[[2rnr]] – hTFIIE C terminal + TFIIH PH domain- NMR<br />
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**[[2rnr]] – hTFIIE C terminal + TFIIH PH domain- NMR<br />
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'''TFIIF'''
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*TFIIF
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[[1f3u]] – hTFIIF<br />
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**[[1f3u]] – hTFIIF<br />
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[[1nha]] – hTFIIF C terminal - NMR<br />
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**[[1nha]] – hTFIIF C terminal - NMR<br />
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[[1i27]] – hTFIIF C terminal (mutant)<br />
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**[[1i27]] – hTFIIF C terminal (mutant)<br />
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[[1j2x]] – hTFIIF C terminal + RNA polymerase CTD phosphatase peptide<br />
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**[[1j2x]] – hTFIIF C terminal + RNA polymerase CTD phosphatase peptide<br />
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[[1onv]] – hTFIIF C terminal + serine phosphatase peptide - NMR<br />
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**[[1onv]] – hTFIIF C terminal + serine phosphatase peptide - NMR<br />
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[[2k7l]] – hTFIIF C terminal + FCP1 peptide - NMR<br />
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**[[2k7l]] – hTFIIF C terminal + FCP1 peptide - NMR<br />
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}}
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</StructureSection>
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[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 10:17, 15 December 2014

Structure of human TFIIB (grey) complex with TATA-binding protein (green) and DNA (PDB entry 1vol)

Drag the structure with the mouse to rotate

3D structures of transcription initiation factors

Updated on 15-December-2014

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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