Tubulin

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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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{{#tree:id=OrganizedByTopic|openlevels=0|
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===α-tubulin===
+
*α-tubulin
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[[2bto]] – PdTUBA+thioredoxin 1 – ''Prosthecobacter dejongeii''<br />
+
**[[2bto]] – PdTUBA+thioredoxin 1 – ''Prosthecobacter dejongeii''<br />
-
[[2e4h]] – hTUBA C terminal + restin CAP-Gly domain 2 – human<br />
+
**[[2e4h]] – hTUBA C terminal + restin CAP-Gly domain 2 – human<br />
-
===α-tubulin + β-tubulin===
+
*α-tubulin + β-tubulin
-
[[3hkb]], [[3hkc]], [[3hkd]], [[3hke]], [[3n2g]], [[3n2k]], [[3ryc]], [[3ryf]], [[3ryh]], [[3ryi]] – sTUBA+sTUBB+stathmin-like protein B3 – sheep<br />
+
**[[3hkb]], [[3hkc]], [[3hkd]], [[3hke]], [[3n2g]], [[3n2k]], [[3ryc]], [[3ryf]], [[3ryh]], [[3ryi]] – sTUBA+sTUBB+stathmin-like protein B3 – sheep<br />
-
[[4f61]] - sTUBA+sTUBB+stathmin-like protein R4<br />
+
**[[4f61]] - sTUBA+sTUBB+stathmin-like protein R4<br />
-
[[3ut5]] - sTUBA+sTUBB+stathmin-like protein B3 + vinca peptide<br />
+
**[[3ut5]] - sTUBA+sTUBB+stathmin-like protein B3 + vinca peptide<br />
-
[[4eb6]] - sTUBA+sTUBB+stathmin-4<br />
+
**[[4eb6]] - sTUBA+sTUBB+stathmin-4<br />
-
[[4drx]] - sTUBA+sTUBB + ankyrin repeat protein<br />
+
**[[4drx]] - sTUBA+sTUBB + ankyrin repeat protein<br />
-
[[4f6r]] - sTUBA+sTUBB+stathmin-like protein R1 + ankyrin repeat protein<br />
+
**[[4f6r]] - sTUBA+sTUBB+stathmin-like protein R1 + ankyrin repeat protein<br />
-
[[2wbe]] – bTUBA1D+bTUBB2B+kinesin+AMPPNP – bovine<br />
+
**[[2wbe]] – bTUBA1D+bTUBB2B+kinesin+AMPPNP – bovine<br />
-
[[3dco]] - bTUBA+bTUBB+kinesin-like NOD<br />
+
**[[3dco]] - bTUBA+bTUBB+kinesin-like NOD<br />
-
[[4ck5]], [[4kc6]], [[4kc7]] - bTUBA+bTUBB+kinesin-like KIF11 motor domain<br />
+
**[[4ck5]], [[4kc6]], [[4kc7]] - bTUBA+bTUBB+kinesin-like KIF11 motor domain<br />
-
[[1tvk]] - bTUBA+bTUBB+GDP+GTP+Epothilone A – electron crystallography<br />
+
**[[1tvk]] - bTUBA+bTUBB+GDP+GTP+Epothilone A – electron crystallography<br />
-
[[3iz0]] - bTUBA+bTUBB+hNDC80/SPC25+hNUF2/SPC24 – electron microscopy<br />
+
**[[3iz0]] - bTUBA+bTUBB+hNDC80/SPC25+hNUF2/SPC24 – electron microscopy<br />
-
[[3edl]] - bTUBA1D+bTUBB2B+kinesin motor domain<br />
+
**[[3edl]] - bTUBA1D+bTUBB2B+kinesin motor domain<br />
-
[[2xrp]] - bTUBA1D+bTUBB2B+doublecortin <br />
+
**[[2xrp]] - bTUBA1D+bTUBB2B+doublecortin <br />
-
[[3du7]], [[3e22]], [[1z2b]], [[1sa0]], [[1sa1]] – bTUBA1C+bTUBB2B+stathmin-like protein B3<br />
+
**[[3du7]], [[3e22]], [[1z2b]], [[1sa0]], [[1sa1]] – bTUBA1C+bTUBB2B+stathmin-like protein B3<br />
-
[[1ffx]] - bTUBA+bTUBB+stathmin-like protein B3<br />
+
**[[1ffx]] - bTUBA+bTUBB+stathmin-like protein B3<br />
-
[[4o2a]] - bTUBA+bTUBB+stathmin-like protein B3 + TUB-Tyr ligase<br />
+
**[[4o2a]] - bTUBA+bTUBB+stathmin-like protein B3 + TUB-Tyr ligase<br />
-
[[4o2b]] - bTUBA+bTUBB+stathmin-like protein B3 + TUB-Tyr ligase + colchicine<br />
+
**[[4o2b]] - bTUBA+bTUBB+stathmin-like protein B3 + TUB-Tyr ligase + colchicine<br />
-
[[4o4h]] - bTUBA+bTUBB+stathmin-like protein B3 + TUB-Tyr ligase + laulimalide<br />
+
**[[4o4h]] - bTUBA+bTUBB+stathmin-like protein B3 + TUB-Tyr ligase + laulimalide<br />
-
[[4o4i]] - bTUBA+bTUBB+stathmin-like protein B3 + TUB-Tyr ligase + epothilone + laulimalide<br />
+
**[[4o4i]] - bTUBA+bTUBB+stathmin-like protein B3 + TUB-Tyr ligase + epothilone + laulimalide<br />
-
[[4o4j]] - bTUBA+bTUBB+stathmin-like protein B3 + TUB-Tyr ligase + peloruside<br />
+
**[[4o4j]] - bTUBA+bTUBB+stathmin-like protein B3 + TUB-Tyr ligase + peloruside<br />
-
[[4o4l]] - bTUBA+bTUBB+stathmin-like protein B3 + TUB-Tyr ligase + peloruside + epothilone<br />
+
**[[4o4l]] - bTUBA+bTUBB+stathmin-like protein B3 + TUB-Tyr ligase + peloruside + epothilone<br />
-
[[1jff]] - bTUBA+bTUBB<br />
+
**[[1jff]] - bTUBA+bTUBB<br />
-
[[4hna]] - bTUBA+bTUBB + kinesin heavy chain + ankyrin repeat protein<br />
+
**[[4hna]] - bTUBA+bTUBB + kinesin heavy chain + ankyrin repeat protein<br />
-
[[4ihj]] - bTUBA+bTUBB+stathmin-like protein B3 + tubulin tyrosine ligase + ADP<br />
+
**[[4ihj]] - bTUBA+bTUBB+stathmin-like protein B3 + tubulin tyrosine ligase + ADP<br />
-
[[4iij]], [[4i55]] - bTUBA+bTUBB+stathmin-like protein B3 + tubulin tyrosine ligase <br />
+
**[[4iij]], [[4i55]] - bTUBA+bTUBB+stathmin-like protein B3 + tubulin tyrosine ligase <br />
-
[[3j1t]], [[3j1u]] - bTUBA+bTUBB+ dyenin<br />
+
**[[3j1t]], [[3j1u]] - bTUBA+bTUBB+ dyenin<br />
-
[[3j2u]] - bTUBA+bTUBB+kinesin-like KLP10A head domain<br />
+
**[[3j2u]] - bTUBA+bTUBB+kinesin-like KLP10A head domain<br />
-
[[4i50]], [[4i4t]] - bTUBA+bTUBB+stathmin-like protein B3 + tubulin tyrosine ligase + anti-cancer agent<br />
+
**[[4i50]], [[4i4t]] - bTUBA+bTUBB+stathmin-like protein B3 + tubulin tyrosine ligase + anti-cancer agent<br />
-
[[2p4n]] - hTUBA+hTUBB+kinesin heavy chain<br />
+
**[[2p4n]] - hTUBA+hTUBB+kinesin heavy chain<br />
-
[[2hxf]] - pTUBA+pTUBB+kinesin-like KIF1A+AMPPNP – pig<br />
+
**[[2hxf]] - pTUBA+pTUBB+kinesin-like KIF1A+AMPPNP – pig<br />
-
[[2hxh]] - pTUBA+pTUBB+kinesin-like KIF1A+ADP<br />
+
**[[2hxh]] - pTUBA+pTUBB+kinesin-like KIF1A+ADP<br />
-
[[1ia0]] - pTUBA+pTUBB+kinesin-like KIF1A+ATP<br />
+
**[[1ia0]] - pTUBA+pTUBB+kinesin-like KIF1A+ATP<br />
-
[[4abo]] - pTUBA+pTUBB+ microtubule integrity protein MAL3<br />
+
**[[4abo]] - pTUBA+pTUBB+ microtubule integrity protein MAL3<br />
-
[[1tub]] - pTUBA+pTUBB – electron diffraction<br />
+
**[[1tub]] - pTUBA+pTUBB – electron diffraction<br />
-
[[4aqv]], [[4aqw]] - bTUBA+bTUBB+kinesin-like KIF11 – Cryo EM<br />
+
**[[4aqv]], [[4aqw]] - bTUBA+bTUBB+kinesin-like KIF11 – Cryo EM<br />
-
[[4atu]] - bTUBA1D+bTUBB2B+doublecortin – Cryo EM<br />
+
**[[4atu]] - bTUBA1D+bTUBB2B+doublecortin – Cryo EM<br />
-
[[4atx]] - bTUBA1D+bTUBB2B+kinesin motor domain – Cryo EM<br />
+
**[[4atx]] - bTUBA1D+bTUBB2B+kinesin motor domain – Cryo EM<br />
-
[[2btq]] – PdTUBA+PdTUBB<br />
+
**[[2btq]] – PdTUBA+PdTUBB<br />
-
[[4ffb]] - TUBA+TUBB (mutant) + protein STU2 - yeast
+
**[[4ffb]] - TUBA+TUBB (mutant) + protein STU2 - yeast
-
===γ-tubulin===
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*γ-tubulin
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[[3cb2]] – hTUBG1+GDP<br />
+
**[[3cb2]] – hTUBG1+GDP<br />
-
[[1z5v]] - hTUBG1+GTPgS<br />
+
**[[1z5v]] - hTUBG1+GTPgS<br />
-
[[1z5w]] - hTUBG1+GTP<br />
+
**[[1z5w]] - hTUBG1+GTP<br />
-
[[3rip]] – hTUBG4<br />
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**[[3rip]] – hTUBG4<br />
-
=== FtsZ ===
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* FtsZ
-
[[2vxy]], [[2vam]] – BsFtsZ - ''Bacillus subtilis''<br />
+
**[[2vxy]], [[2vam]] – BsFtsZ - ''Bacillus subtilis''<br />
-
[[2ve8]] – PaFtsZ gamma domain – ''Pseudomonas aeruginosa''<br />
+
**[[2ve8]] – PaFtsZ gamma domain – ''Pseudomonas aeruginosa''<br />
-
[[2r6r]]– AaFtsZ - ''Aquifex aeolicus''<br />
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**[[2r6r]]– AaFtsZ - ''Aquifex aeolicus''<br />
-
[[1w59]], [[1fsz]] – MjFtsZ - ''Methancaldococcus jannaschii''<br />
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**[[1w59]], [[1fsz]] – MjFtsZ - ''Methancaldococcus jannaschii''<br />
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[[1w5e]], [[1w5f]] – MjFtsZ (mutant) <br />
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**[[1w5e]], [[1w5f]] – MjFtsZ (mutant) <br />
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[[3v3t]] – FtsZ (mutant) – ''Clostridium botulinum''<br />
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**[[3v3t]] – FtsZ (mutant) – ''Clostridium botulinum''<br />
-
[[3zid]] – FtsZ – ''Methanosaeta thermophila''<br />
+
**[[3zid]] – FtsZ – ''Methanosaeta thermophila''<br />
-
[[3vo9]], [[3vpa]] - SaFtsZ – ''Staphylococcus aureus''<br />
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**[[3vo9]], [[3vpa]] - SaFtsZ – ''Staphylococcus aureus''<br />
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[[3wgj]], [[3wgk]] – SaFtsZ (mutant) <br />
+
**[[3wgj]], [[3wgk]] – SaFtsZ (mutant) <br />
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===FtsZ complexes===
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*FtsZ complexes
-
 
+
-
[[2rhh]], [[2rhj]] – BsFtsZ+SO4 <br />
+
-
[[2rhl]] - BsFtsZ+GDP<br />
+
-
[[2rho]] - BsFtsZ+GDP+GTP-gamma-S<br />
+
-
[[2ve9]] - PaFtsZ gamma domain+DNA<br />
+
-
[[2vaw]] – PaFtsZ+GDP<br />
+
-
[[1ofu]] - PaFtsZ+SULA<br />
+
-
[[2r75]] - AaFtsZ+8-morpholino-GTP <br />
+
-
[[2q1x]], [[1rq2]] - MtFtsZ+citrate – ''Mycobacterium tuberculosis''<br />
+
-
[[2q1y]], [[1rlu]] - MtFtsZ+GTP-gamma-S<br />
+
-
[[1rq7]], [[4kwe]] - MtFtsZ+GDP<br />
+
-
[[2vap]] – MjFtsZ+GDP <br />
+
-
[[1w58]] - MjFtsZ+GMPCPP<br />
+
-
[[1w5a]] - MjFtsZ+MgGTP<br />
+
-
[[1w5b]] - MjFtsZ+GTP<br />
+
-
[[4b45]] – HvFtsZ + GTP-γS – ''Haloferax volcanii''<br />
+
-
[[3vo8]], [[3voa]] - SaFtsZ + GDP <br />
+
-
[[3wgl]] – SaFtsZ (mutant) + GDP<br />
+
-
[[3wgn]] – SaFtsZ + GTP-γS<br />
+
-
[[3wgm]] – SaFtsZ (mutant) + GTP<br />
+
-
[[3vob]] - SaFtsZ + GDP + benzamide derivative<br />
+
-
[[4dxd]] - SaFtsZ + antibiotic <br />
+
-
[[4b46]] - HvFtsZ + GDP <br />
+
-
[[4m8i]] - SeFtsZ + GDP – ''Staphylococcus epidermitis''<br />
+
 +
**[[2rhh]], [[2rhj]] – BsFtsZ+SO4 <br />
 +
**[[2rhl]] - BsFtsZ+GDP<br />
 +
**[[2rho]] - BsFtsZ+GDP+GTP-gamma-S<br />
 +
**[[2ve9]] - PaFtsZ gamma domain+DNA<br />
 +
**[[2vaw]] – PaFtsZ+GDP<br />
 +
**[[1ofu]] - PaFtsZ+SULA<br />
 +
**[[2r75]] - AaFtsZ+8-morpholino-GTP <br />
 +
**[[2q1x]], [[1rq2]] - MtFtsZ+citrate – ''Mycobacterium tuberculosis''<br />
 +
**[[2q1y]], [[1rlu]] - MtFtsZ+GTP-gamma-S<br />
 +
**[[1rq7]], [[4kwe]] - MtFtsZ+GDP<br />
 +
**[[2vap]] – MjFtsZ+GDP <br />
 +
**[[1w58]] - MjFtsZ+GMPCPP<br />
 +
**[[1w5a]] - MjFtsZ+MgGTP<br />
 +
**[[1w5b]] - MjFtsZ+GTP<br />
 +
**[[4b45]] – HvFtsZ + GTP-γS – ''Haloferax volcanii''<br />
 +
**[[3vo8]], [[3voa]] - SaFtsZ + GDP <br />
 +
**[[3wgl]] – SaFtsZ (mutant) + GDP<br />
 +
**[[3wgn]] – SaFtsZ + GTP-γS<br />
 +
**[[3wgm]] – SaFtsZ (mutant) + GTP<br />
 +
**[[3vob]] - SaFtsZ + GDP + benzamide derivative<br />
 +
**[[4dxd]] - SaFtsZ + antibiotic <br />
 +
**[[4b46]] - HvFtsZ + GDP <br />
 +
**[[4m8i]] - SeFtsZ + GDP – ''Staphylococcus epidermitis''<br />
 +
}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 07:15, 16 December 2014

Template:STRUCTURE 1z5w

Tubulin (TUB) is a constituent of microtubules in eukaryotes. Microtubules are assembled from dimers of α-tubulin (TUBA) and β-tubulin (TUBB) bound to GTP. γ-tubulin (TUBG) is part of the nucleation of microtubules. Human TUB contains several numbered subtypes. FtsZ (Filamenting temperature-sensitive mutant Z) is a prokaryotic homologue of TUB.

3D Structures of Tubulin

Updated on 16-December-2014

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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