This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


UDP-galactose 4-epimerase

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 2: Line 2:
'''UDP-galactose 4-epimerase''' (GalE) reversibly converts UDP-galactose to UDP-glucose. GalE catalyzes the last step in galactose metabolism. GalE uses NAD+ as a cofactor.
'''UDP-galactose 4-epimerase''' (GalE) reversibly converts UDP-galactose to UDP-glucose. GalE catalyzes the last step in galactose metabolism. GalE uses NAD+ as a cofactor.
 +
</StructureSection>
==3D structures of UDP-galactose 4 epimerase==
==3D structures of UDP-galactose 4 epimerase==
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
 +
{{#tree:id=OrganizedByTopic|openlevels=0|
-
===GalE with no ligand===
+
*UDP-galactose 4-epimerase with no ligand
-
[[1ek5]] - hGalE + NAD - human<br />
+
**[[1ek5]] - hGalE + NAD - human<br />
-
[[2c20]] - GalE + NAD – ''Bacillus anthracis''<br />
+
**[[2c20]] - GalE + NAD – ''Bacillus anthracis''<br />
-
[[2p5u]], [[2p5y]] - GalE + NAD – ''Thermus thermophilus''<br />
+
**[[2p5u]], [[2p5y]] - GalE + NAD – ''Thermus thermophilus''<br />
-
[[3enk]] - GalE + NAD – ''Burkholderia pseudo mallei''<br />
+
**[[3enk]] - GalE + NAD – ''Burkholderia pseudo mallei''<br />
-
[[3icp]], [[3ko8]] - PcGalE + NAD – ''Pyrobaculum calidifontis''<br />
+
**[[3icp]], [[3ko8]] - PcGalE + NAD – ''Pyrobaculum calidifontis''<br />
-
===GalE complexes===
+
*UDP-galactose 4-epimerase complexes
-
 
+
-
[[1nah]], [[1nai]] – EcGalE + NAD + UDP – ''Escherichia coli''<br />
+
-
[[1gy8]] - EcGalE (mutant) + NAD + UDP <br />
+
-
[[1xel]], [[1udb]], [[1a9y]] - EcGalE + NAD + UDP-glucose<br />
+
-
[[1a9z]], [[1lrl]] - EcGalE (mutant) + NAD + UDP-glucose<br />
+
-
[[1uda]] - EcGalE + NAD + UDP-galactose<br />
+
-
[[1lrj]] - EcGalE + NAD + UDP-acetylglucosamine<br />
+
-
[[1lrj]], [[1lrk]] - EcGalE (mutant) + NAD + UDP-acetylglucosamine<br />
+
-
[[1udc]] - EcGalE + NAD + UDP-mannose<br />
+
-
[[1kvr]], [[1kvs]], [[1kvt]], [[1kvu]], [[1kvq]] – EcGalE (mutant) + NAD + UDP-phenol<br />
+
-
[[2udp]] - EcGalE + NAD + UDP-phenol<br />
+
-
[[1ek6]] - hGalE + NAD + UDP-glucose<br />
+
-
[[1hzj]] - hGalE + NAD + UDP-glucosamine<br />
+
-
[[1i3k]] - hGalE (mutant) + NAD + UDP-glucose<br />
+
-
[[1i3l]], [[2cnb]] - hGalE (mutant) + NAD + UDP-galactose<br />
+
-
[[1i3m]], [[1i3n]] - hGalE (mutant) + NAD + UDP-acetylglucosamine<br />
+
-
[[3aw9]] - PcGalE (mutant) + NAD + UDP-galactopyranose <br />
+
 +
**[[1nah]], [[1nai]] – EcGalE + NAD + UDP – ''Escherichia coli''<br />
 +
**[[1gy8]] - EcGalE (mutant) + NAD + UDP <br />
 +
**[[1xel]], [[1udb]], [[1a9y]] - EcGalE + NAD + UDP-glucose<br />
 +
**[[1a9z]], [[1lrl]] - EcGalE (mutant) + NAD + UDP-glucose<br />
 +
**[[1uda]] - EcGalE + NAD + UDP-galactose<br />
 +
**[[1lrj]] - EcGalE + NAD + UDP-acetylglucosamine<br />
 +
**[[1lrj]], [[1lrk]] - EcGalE (mutant) + NAD + UDP-acetylglucosamine<br />
 +
**[[1udc]] - EcGalE + NAD + UDP-mannose<br />
 +
**[[1kvr]], [[1kvs]], [[1kvt]], [[1kvu]], [[1kvq]] – EcGalE (mutant) + NAD + UDP-phenol<br />
 +
**[[2udp]] - EcGalE + NAD + UDP-phenol<br />
 +
**[[1ek6]] - hGalE + NAD + UDP-glucose<br />
 +
**[[1hzj]] - hGalE + NAD + UDP-glucosamine<br />
 +
**[[1i3k]] - hGalE (mutant) + NAD + UDP-glucose<br />
 +
**[[1i3l]], [[2cnb]] - hGalE (mutant) + NAD + UDP-galactose<br />
 +
**[[1i3m]], [[1i3n]] - hGalE (mutant) + NAD + UDP-acetylglucosamine<br />
 +
**[[3aw9]] - PcGalE (mutant) + NAD + UDP-galactopyranose <br />
 +
}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 07:57, 17 December 2014

Structure of UDP-galactose 4 epimerase complex with NAD, UDP (stick model), PEG and Na+1 (purple) ions (PDB entry 1nah)

Drag the structure with the mouse to rotate

3D structures of UDP-galactose 4 epimerase

Updated on 17-December-2014

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

Personal tools