4ql1

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'''Unreleased structure'''
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==Crystal structure of human WDR5 in complex with compound OICR-9429==
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<StructureSection load='4ql1' size='340' side='right' caption='[[4ql1]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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The entry 4ql1 is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4ql1]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QL1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QL1 FirstGlance]. <br>
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Authors: Dong, A., Dombrovski, L., Walker, J.R., Getlik, M., Kuznetsova, E., Smil, D., Barsyte, D., Li, F., Poda, G., Senisterra, G., Marcellus, R., Al-Awar, R., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Brown, P.J., Schapira, M., Vedadi, M., Wu, H., Structural Genomics Consortium (SGC)
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=35Q:N-{4-(4-METHYLPIPERAZIN-1-YL)-3-[(TETRAHYDRO-2H-PYRAN-4-YLAMINO)METHYL]BIPHENYL-3-YL}-6-OXO-4-(TRIFLUOROMETHYL)-1,6-DIHYDROPYRIDINE-3-CARBOXAMIDE'>35Q</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ql1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ql1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ql1 RCSB], [http://www.ebi.ac.uk/pdbsum/4ql1 PDBsum]</span></td></tr>
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Description:
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</table>
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__TOC__
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</StructureSection>
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[[Category: Al-Awar, R]]
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[[Category: Arrowsmith, C H]]
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[[Category: Barsyte, D]]
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[[Category: Bountra, C]]
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[[Category: Brown, P J]]
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[[Category: Dombrovski, L]]
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[[Category: Dong, A]]
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[[Category: Edwards, A M]]
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[[Category: Getlik, M]]
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[[Category: Kuznetsova, E]]
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[[Category: Li, F]]
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[[Category: Marcellus, R]]
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[[Category: Poda, G]]
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[[Category: Structural genomic]]
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[[Category: Schapira, M]]
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[[Category: Senisterra, G]]
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[[Category: Smil, D]]
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[[Category: Vedadi, M]]
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[[Category: Walker, J R]]
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[[Category: Wu, H]]
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[[Category: Oicr-9429 inhibitor]]
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[[Category: Sgc]]
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[[Category: Transcription-inhibitor complex]]
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[[Category: Wd repeat domain 5]]
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[[Category: Wdr5]]

Revision as of 12:58, 17 December 2014

Crystal structure of human WDR5 in complex with compound OICR-9429

4ql1, resolution 1.50Å

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