1p1y
From Proteopedia
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| - | [[Image:1p1y.gif|left|200px]] | + | [[Image:1p1y.gif|left|200px]] |
| - | + | ||
| - | '''Crystal structure of a continuous three-dimensional DNA lattice from d(GGACAGATGGGAG)''' | + | {{Structure |
| + | |PDB= 1p1y |SIZE=350|CAPTION= <scene name='initialview01'>1p1y</scene>, resolution 2.10Å | ||
| + | |SITE= | ||
| + | |LIGAND= <scene name='pdbligand=MG:MAGNESIUM ION'>MG</scene> | ||
| + | |ACTIVITY= | ||
| + | |GENE= | ||
| + | }} | ||
| + | |||
| + | '''Crystal structure of a continuous three-dimensional DNA lattice from d(GGACAGATGGGAG)''' | ||
| + | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1P1Y is a [ | + | 1P1Y is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P1Y OCA]. |
==Reference== | ==Reference== | ||
| - | Crystal structure of a continuous three-dimensional DNA lattice., Paukstelis PJ, Nowakowski J, Birktoft JJ, Seeman NC, Chem Biol. 2004 Aug;11(8):1119-26. PMID:[http:// | + | Crystal structure of a continuous three-dimensional DNA lattice., Paukstelis PJ, Nowakowski J, Birktoft JJ, Seeman NC, Chem Biol. 2004 Aug;11(8):1119-26. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15324813 15324813] |
[[Category: Protein complex]] | [[Category: Protein complex]] | ||
[[Category: Birktoft, J J.]] | [[Category: Birktoft, J J.]] | ||
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[[Category: MG]] | [[Category: MG]] | ||
[[Category: continuous three-dimensional dna lattice]] | [[Category: continuous three-dimensional dna lattice]] | ||
| - | [[Category: parallel-stranded base | + | [[Category: parallel-stranded base pair]] |
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:18:43 2008'' |
Revision as of 11:18, 20 March 2008
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| , resolution 2.10Å | |||||||
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| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal structure of a continuous three-dimensional DNA lattice from d(GGACAGATGGGAG)
Overview
DNA has proved to be a versatile material for the rational design and assembly of nanometer scale objects. Here we report the crystal structure of a continuous three-dimensional DNA lattice formed by the self-assembly of a DNA 13-mer. The structure consists of stacked layers of parallel helices with adjacent layers linked through parallel-stranded base pairing. The hexagonal lattice geometry contains solvent channels that appear large enough to allow 3'-linked guest molecules into the crystal. We have successfully used these parallel base pairs to design and produce crystals with greatly enlarged solvent channels. This lattice may have applications as a molecular scaffold for structure determination of guest molecules, as a molecular sieve, or in the assembly of molecular electronics. Predictable non-Watson-Crick base pairs, like those described here, may present a new tool in structural DNA nanotechnology.
About this Structure
1P1Y is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.
Reference
Crystal structure of a continuous three-dimensional DNA lattice., Paukstelis PJ, Nowakowski J, Birktoft JJ, Seeman NC, Chem Biol. 2004 Aug;11(8):1119-26. PMID:15324813
Page seeded by OCA on Thu Mar 20 13:18:43 2008
