3ii0
From Proteopedia
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| - | + | ==Crystal structure of human Glutamate oxaloacetate transaminase 1 (GOT1)== | |
| - | + | <StructureSection load='3ii0' size='340' side='right' caption='[[3ii0]], [[Resolution|resolution]] 2.05Å' scene=''> | |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3ii0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3II0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3II0 FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=TAR:D(-)-TARTARIC+ACID'>TAR</scene></td></tr> | ||
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ajs|1ajs]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GOT1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aspartate_transaminase Aspartate transaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.1 2.6.1.1] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ii0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ii0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ii0 RCSB], [http://www.ebi.ac.uk/pdbsum/3ii0 PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ii/3ii0_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | == | + | ==See Also== |
| - | [[ | + | *[[Aspartate Aminotransferase|Aspartate Aminotransferase]] |
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Aspartate transaminase]] | [[Category: Aspartate transaminase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Arrowsmith, C H | + | [[Category: Arrowsmith, C H]] |
| - | [[Category: Bountra, C | + | [[Category: Bountra, C]] |
| - | [[Category: Bray, J E | + | [[Category: Bray, J E]] |
| - | [[Category: Chaikuad, A | + | [[Category: Chaikuad, A]] |
| - | [[Category: Cooper, C | + | [[Category: Cooper, C]] |
| - | [[Category: Delft, F von | + | [[Category: Delft, F von]] |
| - | [[Category: Edwards, A | + | [[Category: Edwards, A]] |
| - | [[Category: Kavanagh, K L | + | [[Category: Kavanagh, K L]] |
| - | [[Category: Muniz, J | + | [[Category: Muniz, J]] |
| - | [[Category: Oppermann, U | + | [[Category: Oppermann, U]] |
| - | [[Category: Pilka, E | + | [[Category: Pilka, E]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Ugochukwu, E | + | [[Category: Ugochukwu, E]] |
| - | [[Category: Weigelt, J | + | [[Category: Weigelt, J]] |
| - | [[Category: Yue, W W | + | [[Category: Yue, W W]] |
[[Category: Amino acid metabolism]] | [[Category: Amino acid metabolism]] | ||
[[Category: Aminotransferase]] | [[Category: Aminotransferase]] | ||
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[[Category: Pyridoxal phosphate-dependent enzyme]] | [[Category: Pyridoxal phosphate-dependent enzyme]] | ||
[[Category: Sgc]] | [[Category: Sgc]] | ||
| - | [[Category: Structural genomic]] | ||
| - | [[Category: Structural genomics consortium]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
[[Category: Urea and tricarboxylic acid cycle]] | [[Category: Urea and tricarboxylic acid cycle]] | ||
Revision as of 06:18, 18 December 2014
Crystal structure of human Glutamate oxaloacetate transaminase 1 (GOT1)
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Categories: Aspartate transaminase | Homo sapiens | Arrowsmith, C H | Bountra, C | Bray, J E | Chaikuad, A | Cooper, C | Delft, F von | Edwards, A | Kavanagh, K L | Muniz, J | Oppermann, U | Pilka, E | Structural genomic | Ugochukwu, E | Weigelt, J | Yue, W W | Amino acid metabolism | Aminotransferase | Aspartate aminotransferase 1 | Glutamate oxaloacetate transaminase 1 | Phosphoprotein | Pyridoxal phosphate | Pyridoxal phosphate-dependent enzyme | Sgc | Transferase | Urea and tricarboxylic acid cycle
