3i0a

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{{STRUCTURE_3i0a| PDB=3i0a | SCENE= }}
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==Crystal structure of Siderocalin (NGAL, Lipocalin 2) K134A mutant complexed with Ferric Enterobactin==
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===Crystal structure of Siderocalin (NGAL, Lipocalin 2) K134A mutant complexed with Ferric Enterobactin===
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<StructureSection load='3i0a' size='340' side='right' caption='[[3i0a]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3i0a]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I0A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3I0A FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2DS:N-[(2,3-DIHYDROXYPHENYL)CARBONYL]-O-[(2R)-2-{[(2,3-DIHYDROXYPHENYL)CARBONYL]AMINO}-3-HYDROXYPROPANOYL]-L-SERINE'>2DS</scene>, <scene name='pdbligand=3ET:O-[(2R)-2-AMINO-3-(D-SERYLOXY)PROPANOYL]-N-[(2,3-DIHYDROXYPHENYL)CARBONYL]-L-SERINE'>3ET</scene>, <scene name='pdbligand=DBH:2,3-DIHYDROXY-BENZOIC+ACID'>DBH</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MCJ:N-[(2,3-DIHYDROXYPHENYL)CARBONYL]-O-[(2S)-2-{[(2,3-DIHYDROXYPHENYL)CARBONYL]AMINO}-3-({N-[(2,3-DIHYDROXYPHENYL)CARBONYL]-L-SERYL}OXY)PROPANOYL]-D-SERINE'>MCJ</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3cmp|3cmp]], [[3hwd|3hwd]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HNL, LCN2, NGAL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3i0a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i0a OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3i0a RCSB], [http://www.ebi.ac.uk/pdbsum/3i0a PDBsum]</span></td></tr>
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</table>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i0/3i0a_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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<div style="clear:both"></div>
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==About this Structure==
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==See Also==
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[[3i0a]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I0A OCA].
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*[[Neutrophil gelatinase-associated lipocalin|Neutrophil gelatinase-associated lipocalin]]
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Clifton, M C.]]
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[[Category: Clifton, M C]]
[[Category: 25 kda alpha-2-microglobulin-related subunit of mmp-9]]
[[Category: 25 kda alpha-2-microglobulin-related subunit of mmp-9]]
[[Category: Antimicrobial protein]]
[[Category: Antimicrobial protein]]

Revision as of 06:28, 18 December 2014

Crystal structure of Siderocalin (NGAL, Lipocalin 2) K134A mutant complexed with Ferric Enterobactin

3i0a, resolution 2.60Å

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