1pbo

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1pbo.jpg|left|200px]]<br /><applet load="1pbo" size="350" color="white" frame="true" align="right" spinBox="true"
+
[[Image:1pbo.jpg|left|200px]]
-
caption="1pbo, resolution 2.2&Aring;" />
+
 
-
'''COMPLEX OF BOVINE ODORANT BINDING PROTEIN (OBP) WITH A SELENIUM CONTAINING ODORANT'''<br />
+
{{Structure
 +
|PDB= 1pbo |SIZE=350|CAPTION= <scene name='initialview01'>1pbo</scene>, resolution 2.2&Aring;
 +
|SITE=
 +
|LIGAND= <scene name='pdbligand=SES:2-AMINO-4-BUTYL-5-PROPYLSELENAZOLE'>SES</scene>
 +
|ACTIVITY=
 +
|GENE=
 +
}}
 +
 
 +
'''COMPLEX OF BOVINE ODORANT BINDING PROTEIN (OBP) WITH A SELENIUM CONTAINING ODORANT'''
 +
 
==Overview==
==Overview==
Line 7: Line 16:
==About this Structure==
==About this Structure==
-
1PBO is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] with <scene name='pdbligand=SES:'>SES</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PBO OCA].
+
1PBO is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PBO OCA].
==Reference==
==Reference==
-
The three-dimensional structure of bovine odorant binding protein and its mechanism of odor recognition., Bianchet MA, Bains G, Pelosi P, Pevsner J, Snyder SH, Monaco HL, Amzel LM, Nat Struct Biol. 1996 Nov;3(11):934-9. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=8901871 8901871]
+
The three-dimensional structure of bovine odorant binding protein and its mechanism of odor recognition., Bianchet MA, Bains G, Pelosi P, Pevsner J, Snyder SH, Monaco HL, Amzel LM, Nat Struct Biol. 1996 Nov;3(11):934-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8901871 8901871]
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Single protein]]
[[Category: Single protein]]
Line 22: Line 31:
[[Category: transport]]
[[Category: transport]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:27:08 2008''
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:22:24 2008''

Revision as of 11:22, 20 March 2008

Image:1pbo.jpg


PDB ID 1pbo

Drag the structure with the mouse to rotate
, resolution 2.2Å
Ligands:
Coordinates: save as pdb, mmCIF, xml



COMPLEX OF BOVINE ODORANT BINDING PROTEIN (OBP) WITH A SELENIUM CONTAINING ODORANT


Overview

Odorant binding protein (OBP) is the major odorant binding component of mammalian nasal mucosa. The two structures of bovine OBP reported in this paper (one crystallized as purified and one soaked in the presence of a selenium-containing odorant) show that: (i) the OBP dimer is composed of two compact domains related by an approximate two-fold axis of symmetry; (ii) between residues 122 and 123 the polypeptide chains cross from one domain to the other such that each domain is formed by residues from both monomers; (iii) purified OBP already contains two bound odorant molecules (one per monomer)-odorant binding occurs by replacement of these molecules with the added odorant; and (iv) the structure of the odorant binding site can explain OBP's extraordinarily broad odorant specificity.

About this Structure

1PBO is a Single protein structure of sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

The three-dimensional structure of bovine odorant binding protein and its mechanism of odor recognition., Bianchet MA, Bains G, Pelosi P, Pevsner J, Snyder SH, Monaco HL, Amzel LM, Nat Struct Biol. 1996 Nov;3(11):934-9. PMID:8901871

Page seeded by OCA on Thu Mar 20 13:22:24 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1pbo"
Personal tools