1pcf

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[[Image:1pcf.gif|left|200px]]<br /><applet load="1pcf" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1pcf.gif|left|200px]]
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caption="1pcf, resolution 1.74&Aring;" />
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'''HUMAN TRANSCRIPTIONAL COACTIVATOR PC4 C-TERMINAL DOMAIN'''<br />
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{{Structure
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|PDB= 1pcf |SIZE=350|CAPTION= <scene name='initialview01'>1pcf</scene>, resolution 1.74&Aring;
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|SITE=
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|LIGAND=
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|ACTIVITY=
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|GENE=
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}}
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'''HUMAN TRANSCRIPTIONAL COACTIVATOR PC4 C-TERMINAL DOMAIN'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1PCF is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PCF OCA].
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1PCF is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PCF OCA].
==Reference==
==Reference==
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C-terminal domain of transcription cofactor PC4 reveals dimeric ssDNA binding site., Brandsen J, Werten S, van der Vliet PC, Meisterernst M, Kroon J, Gros P, Nat Struct Biol. 1997 Nov;4(11):900-3. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9360603 9360603]
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C-terminal domain of transcription cofactor PC4 reveals dimeric ssDNA binding site., Brandsen J, Werten S, van der Vliet PC, Meisterernst M, Kroon J, Gros P, Nat Struct Biol. 1997 Nov;4(11):900-3. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9360603 9360603]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: transcriptional cofactor]]
[[Category: transcriptional cofactor]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:27:21 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:22:38 2008''

Revision as of 11:22, 20 March 2008

Image:1pcf.gif


PDB ID 1pcf

Drag the structure with the mouse to rotate
, resolution 1.74Å
Coordinates: save as pdb, mmCIF, xml



HUMAN TRANSCRIPTIONAL COACTIVATOR PC4 C-TERMINAL DOMAIN


Overview

The crystal structure of human replication and transcription cofactor PC4CTD reveals a dimer with two single-stranded (ss)DNA binding channels running in opposite directions to each other. This arrangement suggests a role in establishment or maintenance of melted DNA at promoters or origins of replication.

About this Structure

1PCF is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

C-terminal domain of transcription cofactor PC4 reveals dimeric ssDNA binding site., Brandsen J, Werten S, van der Vliet PC, Meisterernst M, Kroon J, Gros P, Nat Struct Biol. 1997 Nov;4(11):900-3. PMID:9360603

Page seeded by OCA on Thu Mar 20 13:22:38 2008

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