We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.

2m7y

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
{{STRUCTURE_2m7y| PDB=2m7y | SCENE= }}
+
==The Mengovirus Leader protein==
-
===The Mengovirus Leader protein===
+
<StructureSection load='2m7y' size='340' side='right' caption='[[2m7y]], [[NMR_Ensembles_of_Models | 1 NMR models]]' scene=''>
-
 
+
== Structural highlights ==
-
==Function==
+
<table><tr><td colspan='2'>[[2m7y]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mengo_virus Mengo virus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M7Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2M7Y FirstGlance]. <br>
-
[[http://www.uniprot.org/uniprot/POLG_ENMGO POLG_ENMGO]] Capsid proteins VP1, VP2, VP3 and VP4 form a closed capsid enclosing the viral positive strand RNA genome. VP4 lies on the inner surface of the protein shell formed by VP1, VP2 and VP3. All the three latter proteins contain a beta-sheet structure called beta-barrel jelly roll. Together they form an icosahedral capsid (T=3) composed of 60 copies of each VP1, VP2, and VP3, with a diameter of approximately 300 Angstroms. VP1 is situated at the 12 fivefold axes, whereas VP2 and VP3 are located at the quasi-sixfold axes (By similarity). Protein VP0: VP0 precursor is a component of immature procapsids (By similarity). Protein 2B: Affects membrane integrity and cause an increase in membrane permeability (By similarity). Protein 2C: Associates with and induces structural rearrangements of intracellular membranes. It displays RNA-binding, nucleotide binding and NTPase activities (By similarity). Protein 3A, via its hydrophobic domain, serves as membrane anchor (By similarity). Protease 3C: cysteine protease that generates mature viral proteins from the precursor polyprotein. In addition to its proteolytic activity, it binds to viral RNA, and thus influences viral genome replication. RNA and substrate bind cooperatively to the protease (By similarity). RNA-directed RNA polymerase 3D-POL replicates genomic and antigenomic RNA by recognizing replications specific signals (By similarity). Protein 2A: is involved in host translation shutoff. Nuclear localization is required for this function (By similarity).
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
 
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2m7y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m7y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2m7y RCSB], [http://www.ebi.ac.uk/pdbsum/2m7y PDBsum]</span></td></tr>
-
==About this Structure==
+
</table>
-
[[2m7y]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mengo_virus Mengo virus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M7Y OCA].
+
__TOC__
 +
</StructureSection>
[[Category: Mengo virus]]
[[Category: Mengo virus]]
-
[[Category: Cornilescu, C C.]]
+
[[Category: Cornilescu, C C]]
-
[[Category: Davis, V.]]
+
[[Category: Davis, V]]
-
[[Category: Markley, J L.]]
+
[[Category: Markley, J L]]
-
[[Category: Palmenberg, A C.]]
+
[[Category: Palmenberg, A C]]
-
[[Category: Porter, F W.]]
+
[[Category: Porter, F W]]
-
[[Category: Zhao, K Q.]]
+
[[Category: Zhao, K Q]]
[[Category: Cardiovirus]]
[[Category: Cardiovirus]]
[[Category: Viral protein]]
[[Category: Viral protein]]

Revision as of 12:08, 18 December 2014

The Mengovirus Leader protein

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2m7y"
Personal tools